Hypolipidemic Diets and Biliary Lipid Composition

1980 ◽  
pp. 320-323
Author(s):  
G. Schlierf ◽  
A. Stiehl ◽  
C. C. Heuck ◽  
M. Kohlmeier ◽  
P. Oster ◽  
...  
Keyword(s):  
Lipid Composition ◽  
Biliary Lipid ◽  
Biliary Lipid Composition

Effects of sulfobromophthalein excretion on biliary lipid secretion in humans and dogs

1981 ◽  
Vol 240 (1) ◽  
pp. G85-G89
Author(s):  
E. A. Shafter ◽  
R. M. Preshaw
Keyword(s):  
Bile Salt ◽  
Lipid Composition ◽  
Control Period ◽  
Physical Interaction ◽  
Biliary Lipid ◽  
Lipid Secretion ◽  
Maximal Output ◽  
Biliary Lipid Composition ◽  
Molar Percent ◽  
Salt Secretion

The effect of sulfobromophthalein (BSP) on biliary lipid secretion was investigated in 12 cholecystectomized subjects, using a duodenal marker-perfusion technique. A 1-h basal period was followed by intravenous BSP infusion over 3 h, achieving the maximal excretory rate (Tm). The calculated Tm was not different from the measured maximal output. At BSP Tm, bile salt secretion was unchanged, but phospholipid, cholesterol, and bilirubin secretion were markedly reduced. Biliary lipid composition changed accordingly, higher molar percent bile salts but lower phospholipid and cholesterol. In six cholecystectomized dogs with chronic duodenal fistulas, bile was collected directly from the common duct while bile salt secretion was maintained by intravenous taurocholic acid infusion. After a 2-h control period, sufficient BSP was added to create either maximal (Tm) or submaximal conditions. BSP did not alter bile salt secretion but caused a dose-related decrease in phospholipid and cholesterol secretion. Bilirubin excretion was also reduced, whereas bile flow increased. Thus, BSP is hydrocholeretic but decreases phospholipid, cholesterol, and bilirubin secretion in both humans and dogs. The effect on biliary lipid composition is probably through a physical interaction with biliary micelles.

Biliary lipid composition in patients with nonoperated Crohn's disease

1986 ◽  
Vol 31 (1) ◽  
pp. 27-32 ◽  
Author(s):  
P. Rutgeerts ◽  
Y. Ghoos ◽  
G. Vantrappen ◽  
J. Fevery
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Lipid Composition ◽  
Biliary Lipid ◽  
Biliary Lipid Composition

Bile formation and biliary lipid composition under the influence of clofibrate and phenobarbital pretreatment in the rat

1979 ◽  
Vol 308 (2) ◽  
pp. 171-177 ◽  
Author(s):  
Klaus Kutz ◽  
Anne Schulte ◽  
Christa Just ◽  
Holger Lindstaedt ◽  
Bernd Reiter
Keyword(s):  
Lipid Composition ◽  
Biliary Lipid ◽  
Bile Formation ◽  
Biliary Lipid Composition
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