Heterogeneity in Neural Crest Cell Populations

1984 ◽  
pp. 51-62 ◽  
Author(s):  
James A. Weston ◽  
John Girdlestone ◽  
Gary Ciment
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Crest Cell

Analysis of developmentally homogeneous neural crest cell populations in vitro

1981 ◽  
Vol 82 (1) ◽  
pp. 86-94 ◽  
Author(s):  
Jeanne Loring ◽  
Bengt Glimelius ◽  
Carol Erickson ◽  
James A. Weston
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Crest Cell

scholarly journals Sox10ERT2CreERT2mice enable tracing of distinct neural crest cell populations

2015 ◽  
Vol 244 (11) ◽  
pp. 1394-1403 ◽  
Author(s):  
Fenglei He ◽  
Philippe Soriano
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Crest Cell

scholarly journals PDGF function in diverse neural crest cell populations

2010 ◽  
Vol 4 (4) ◽  
pp. 561-566 ◽  
Author(s):  
Christopher L. Smith ◽  
Michelle D. Tallquist
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Crest Cell

Analysis of developmentally homogeneous neural crest cell populations in vitro

1981 ◽  
Vol 82 (1) ◽  
pp. 95-101 ◽  
Author(s):  
Bengt Glimelius ◽  
James A. Weston
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Crest Cell

scholarly journals Early- and late-migrating cranial neural crest cell populations have equivalent developmental potential in vivo

Development ◽  
1997 ◽  
Vol 124 (16) ◽  
pp. 3077-3087 ◽  
Author(s):  
C.V. Baker ◽  
M. Bronner-Fraser ◽  
N.M. Le Douarin ◽  
M.A. Teillet
Keyword(s):  
Neural Crest ◽  
Normal Development ◽  
Neural Crest Cell ◽  
Cell Populations ◽  
Developmental Potential ◽  
Cranial Neural Crest Cell ◽  
Fate Restriction ◽  
Crest Cell

We present the first in vivo study of the long-term fate and potential of early-migrating and late-migrating mesencephalic neural crest cell populations, by performing isochronic and heterochronic quail-to-chick grafts. Both early- and late-migrating populations form melanocytes, neurons, glia, cartilage and bone in isochronic, isotopic chimeras, showing that neither population is lineage-restricted. The early-migrating population distributes both dorsally and ventrally during normal development, while the late-migrating population is confined dorsally and forms much less cartilage and bone. When the late-migrating population is substituted heterochronically for the early-migrating population, it contributes extensively to ventral derivatives such as jaw cartilage and bone. Conversely, when the early-migrating population is substituted heterochronically for the late-migrating population, it no longer contributes to the jaw skeleton and only forms dorsal derivatives. When the late-migrating population is grafted into a late-stage host whose neural crest had previously been ablated, it migrates ventrally into the jaws. Thus, the dorsal fate restriction of the late-migrating mesencephalic neural crest cell population in normal development is due to the presence of earlier-migrating neural crest cells, rather than to any change in the environment or to any intrinsic difference in migratory ability or potential between early- and late-migrating cell populations. These results highlight the plasticity of the neural crest and show that its fate is determined primarily by the environment.

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