The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies

2012 ◽  
pp. 3-25
Author(s):  
Laura S. Schmidt ◽  
Ramaprasad Srinivasan ◽  
W. Marston Linehan
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies ◽  
Genetic Basis

Genetic basis of kidney cancer: a model for developing molecular-targeted therapies

2007 ◽  
Vol 99 (5b) ◽  
pp. 1223-1229 ◽  
Author(s):  
Manish A. Vira ◽  
Kristian R. Novakovic ◽  
Peter A. Pinto ◽  
W. Marston Linehan
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies ◽  
Genetic Basis ◽  
Molecular Targeted Therapies

New targeted therapies in kidney cancer

2021 ◽  
Author(s):  
Karl Mayrhofer ◽  
Dora Niedersüß-Beke
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies

The genetic basis of cancer of kidney cancer: implications for gene-specific clinical management

2005 ◽  
Vol 95 (s2) ◽  
pp. 2-7 ◽  
Author(s):  
W. Marston Linehan ◽  
Robert L. Grubb ◽  
Jonathan A. Coleman ◽  
Berton Zbar ◽  
McClellan M. Walther
Keyword(s):  
Kidney Cancer ◽  
Clinical Management ◽  
Genetic Basis

Targeted Therapies in Kidney Cancer

2015 ◽  
pp. 197-210
Author(s):  
Amparo Sánchez Gastaldo ◽  
Aránzazu González del Alba ◽  
Ignacio Durán
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies

Disease-Modifying Therapies in Neurodegenerative Disorders

2016 ◽  
Author(s):  
Janelle Drouin-Ouellet ◽  
Roger A. Barker
Keyword(s):  
Targeted Therapies ◽  
Neurodegenerative Disorders ◽  
Genetic Basis ◽  
Therapeutic Strategies ◽  
Mutant Huntingtin ◽  
Brain Health ◽  
Disease Modifying Therapies ◽  
Diet And Exercise ◽  
Disease Modifying ◽  
Disease Pathways

The recent identification of the genetic basis of many neurodegenerative disorders (NDDs), coupled with a greater understanding of their pathophysiology, has enabled better therapeutic strategies to be identified and tried. This includes approaches that target critical specific nodes in the disease pathways, for example, agents that modulate levels of mutant huntingtin in Huntington’s disease. In addition to these highly specific targeted therapies, there is also a growing realization that more generic lifestyle therapies influencing whole brain health may also have merit in treating these conditions-such as diet and exercise. This chapter explores the different approaches and agents used to try to modify the course of a range of NDDs, and highlights their progress relative to the clinic and the patients suffering with these currently incurable conditions.

Kidney cancer: Experience of Centro Oncologico Buenos Aires (COBA) with immunotherapy (It) and targeted therapies (TT).

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. e15024-e15024
Author(s):  
A. P. Hunis ◽  
L. A. Reuter ◽  
M. Hunis ◽  
A. Deves
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies ◽  
Buenos Aires ◽  
Cancer Experience

scholarly journals Genetic basis for kidney cancer: opportunity for disease-specific approaches to therapy

2008 ◽  
Vol 8 (6) ◽  
pp. 779-790 ◽  
Author(s):  
Elizabeth Cartwright Pfaffenroth ◽  
W Marston Linehan
Keyword(s):  
Kidney Cancer ◽  
Genetic Basis ◽  
Disease Specific

Targeted therapies for kidney cancer in urologic practice

2007 ◽  
Vol 25 (5) ◽  
pp. 420-432 ◽  
Author(s):  
Naomi B. Haas ◽  
Robert G. Uzzo
Keyword(s):  
Kidney Cancer ◽  
Targeted Therapies
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