Climbing Fibers

2003 ◽  
pp. 69-75
Author(s):  
Orlando J. Castejón
Keyword(s):  
Climbing Fibers

Evidence for a multiple innervation of purkinje cells by climbing fibers in the immature rat cerebellum

1976 ◽  
Vol 7 (6) ◽  
pp. 567-578 ◽  
Author(s):  
Francis Crepel ◽  
Jean Mariani ◽  
Nicole Delhaye-Bouchaud
Keyword(s):  
Purkinje Cells ◽  
Climbing Fibers ◽  
Immature Rat ◽  
Rat Cerebellum

Motor Coding in Floccular Climbing Fibers

2006 ◽  
Vol 95 (4) ◽  
pp. 2342-2351 ◽  
Author(s):  
Beerend Winkelman ◽  
Maarten Frens
Keyword(s):  
Visual Motion ◽  
Inferior Olive ◽  
Motor Behavior ◽  
Climbing Fibers ◽  
Retinal Slip ◽  
Motor Component ◽  
Prepositus Hypoglossi ◽  
Sensorimotor Information ◽  
Sensory Encoding ◽  
Oculomotor Learning

The climbing fibers (CFs) that project from the dorsal cap of the inferior olive (IO) to the flocculus of the cerebellar cortex have been reported to be purely sensory, encoding “retinal slip.” However, a clear oculomotor projection from the nucleus prepositus hypoglossi (NPH) to the IO has been shown. We therefore studied the sensorimotor information that is present in the CF signal. We presented rabbits with visual motion noise stimuli to break up the tight relation between instantaneous retinal slip and eye movement. Strikingly, the information about the motor behavior in the CF signal more than doubled that of the sensory component and was time-locked more tightly. The contribution of oculomotor signals was independently confirmed by analysis of spontaneous eye movements in the absence of visual input. The motor component of the CF code is essential to distinguish unexpected slip from self-generated slip, which is a prerequisite for proper oculomotor learning.

Confocal Laser Scanning Microscopy of Hamster Cerebellum using FM4-64 as Intracellular Staining

1998 ◽  
Vol 4 (S2) ◽  
pp. 1126-1127
Author(s):  
O. Castejón ◽  
P. Sims
Keyword(s):  
Confocal Laser Scanning Microscopy ◽  
Laser Scanning ◽  
Granular Layer ◽  
Fluorescent Dyes ◽  
Laser Scanning Microscopy ◽  
Climbing Fibers ◽  
Confocal Laser Scanning ◽  
Scanning Microscopy ◽  
Confocal Laser ◽  
Fluorescence Signal

Confocal laser scanning microscopy is an excellent method to study nerve cell morphology and the three-dimensional distribution and interrelationship of dentrites and axons in the central nervous system. The cerebellum has been taking as a model of a gray center.The FM4-64, a member of the family of fluorescent dyes, has been applied to the cerebellar cortex to evaluate its properties as an intracellular stain and intracortical tracer. Slabs of hamster cerebellum,5 mm thick, were incubated in 10,30 and 100 μm solutions of FM4-64 in sodium phosphate buffer and observed in a slow scan confocal laser scanning microscope. Mossy and climbing fibers were traced in the cerebellar white and gray substances .They exhibited high fluorescence signal at the level of myelin sheath.Mossy fibers were identified in the granular layer by their typical rosette formation and dichotomous bifurcation pattern. Climbing fibers bundles were observed crossing the granular layer and giving collateral branches around Golgi cell bodies.

scholarly journals Reliable Coding Emerges from Coactivation of Climbing Fibers in Microbands of Cerebellar Purkinje Neurons

2009 ◽  
Vol 29 (34) ◽  
pp. 10463-10473 ◽  
Author(s):  
I. Ozden ◽  
M. R. Sullivan ◽  
H. M. Lee ◽  
S. S.-H. Wang
Keyword(s):  
Climbing Fibers ◽  
Purkinje Neurons ◽  
Cerebellar Purkinje Neurons

Developmental switching of perisomatic innervation from climbing fibers to basket cell fibers in developing cerebellar purkinje cells

2011 ◽  
Vol 71 ◽  
pp. e215
Author(s):  
Ryoichi Ichikawa ◽  
Miwako Yamasaki ◽  
Taisuke Miyazaki ◽  
Haruyuki Tatsumi ◽  
Masahiko Watanabe
Keyword(s):  
Purkinje Cells ◽  
Climbing Fibers ◽  
Basket Cell ◽  
Cerebellar Purkinje Cells
Sign in / Sign up

Export Citation Format

Share Document