Autoimmune Thyroid Disorders in Juvenile Chronic Arthritis and Systemic Lupus Erythematosus

1999 ◽  
pp. 55-60 ◽  
Author(s):  
D. Mihailova ◽  
R. Grigorova ◽  
B. Vassileva ◽  
G. Mladenova ◽  
N. Ivanova ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Thyroid Disorders ◽  
Systemic Lupus ◽  
Autoimmune Thyroid

Connective tissue disease

2013 ◽  
pp. 257-300
Author(s):  
Gavin P Spickett
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Still’S Disease ◽  
Systemic Lupus ◽  
Still's Disease ◽  
Adult Still's Disease ◽  
Immunological Tests

Rheumatoid arthritis: aetiology, clinical features, and immunopathology Rheumatoid arthritis: immunological tests, treatment, and childhood RhA Juvenile chronic arthritis (JCA) and Still’s disease Adult Still’s disease Ankylosing spondylitis (AS) and related spondyloarthropathies SAPHO syndrome Psoriatic arthritis Reactive arthritis (including Reiter’s syndrome) Systemic lupus erythematosus (SLE) and variants...

Thyroid disorders in Chinese patients with systemic lupus erythematosus

1993 ◽  
Vol 13 (1) ◽  
pp. 9-13 ◽  
Author(s):  
R. -T. Tsai ◽  
T. -C. Chang ◽  
C. -R. Wang ◽  
C. -Y. Chuang ◽  
C. -Y. Chen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Chinese Patients ◽  
Thyroid Disorders ◽  
Systemic Lupus

Autoimmune thyroid diseases, autoimmune hepatitis, celiac disease and type 1 diabetes mellitus in pediatric systemic lupus erythematosus: Results from the CARRA Legacy Registry

Lupus ◽  
2020 ◽  
Vol 29 (14) ◽  
pp. 1926-1936
Author(s):  
Ohoud AlAhmed ◽  
Vidya Sivaraman ◽  
Melissa Moore-Clingenpeel ◽  
Stacy P Ardoin ◽  
Sharon Bout-Tabaku ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Pediatric Systemic Lupus Erythematosus ◽  
Over Time ◽  
Lupus Disease Activity

Objective Polyautoimmunity (PA) with systemic lupus erythematosus (SLE) is reported as a poor prognostic factor, but little is known about its effect in childhood-onset SLE (cSLE). We describe PA in cSLE within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry and evaluate its association to lupus disease outcomes. Methods CARRA Legacy Registry is the largest pediatric rheumatology registry that collected data at enrollment and every 6 months thereafter. We describe the co-occurrence of selected autoimmune disorders (autoimmune thyroid diseases, autoimmune hepatitis, celiac disease and type 1 diabetes mellitus) in cSLE. To assess outcomes, we studied measures of lupus disease activity, complications, and patient’s quality of life (QoL). Comparisons by PA status were made using chi-square, Fisher’s exact test, two-sample t-tests, Wilcoxon rank sum tests, and mixed effects models as appropriate. Results 1285 patients met the American College of Rheumatology criteria for SLE. Of those, 388 (30%) had data on comorbidity. The prevalence of PA was 8.8%. Patients with PA reported more hospitalizations and aggressive immunotherapy use. SLEDAI and PGA scores improved over time, but did not differ by PA status. No significant differences were found in QoL measures or their trajectory over time by PA status. Conclusion In cSLE, PA is associated with more hospitalizations and aggressive immunotherapy use. Although lupus disease activity improved over time, patients' QoL neither improved over time nor differed by having other autoimmune disease. Prospective, case-control, long-term follow-up studies on cSLE are needed to validate our results. MeSH Key Indexing Terms Pediatric systemic lupus erythematosus; Autoimmune diseases; Outcome assessment

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