The incidence of thyroid dysfunction in diabetic patients – A study done at a tertiary care center in South India

It has been noted that in the Indian population the incidence of thyroid disorder is common and its incidence rises with advancing age. Screening for thyroid disorder is indicated for the certain high risk patients such as elderly and those already having other endocrinal disorders There are various studies that have shown a finding that a higher than normal prevalence of thyroid disorders in type 2 diabetic patients, of which hypothyroidism is the commonest disorder Owing to this we at the medical college at south India decided to evaluate the occurrence of thyroid dysfunction in patients who have been diagnosed with diabetes mellitus and also to compare the level of thyroid dysfunction in the younger and the older population.Department of surgery, medicine and Pharmacology at Al Azhar Medical College Thodupuzha, Kerala, India for a duration of 3 years on 300 patients. The present study was an observational study during the period of study, the test subjects patients having diabetes mellitus and healthy individuals (Controls)coming for regular health check-up with no co morbidities detected were included in this study as controls.In the non -geriatric age group the mean age was 49.6 years SD + 8.15 years and in the geriatric age group the mean age was 68.78 years SD + 4.83 years. The commonest age group in the study was between the age of 61-70 years with of the study population. The age group in the present study ranged between the age of 30 years and 79 years. The incidence of diabetes mellitus increased with age, but the control of sugars is better with age thyroid dysfunction was as follows 20% had hyperthyroidism (36%) hypothyroidism. There is a linear increase with the prevalence of thyroid disorders with age with a r= 0.77 and p < 0.05.The incidence of thyroid dysfunction also increased with age As compared to the non -geriatric group which was the incidence higher in older age group p < 0.05.This study reveals about at least one in three who have DM are suffering from thyroid dysfunction, that increases with increasing age and uncontrolled sugars in this part of the world, which might warrant routine screening.

Thyroid disorders and development of cognitive impairment: a review study

Dementia is a neurological disorder that is spreading with increasing human lifespan. In this neurological disorder, memory and cognition are declined and eventually impaired. Various factors can be considered as the background of this disorder, one of which is endocrine disorders. Thyroid hormones are involved in various physiological processes in the body; one of the most important of them is neuromodulation. Thyroid disorders, including hyperthyroidism or hypothyroidism, can affect the nervous system and play a role in the development of dementia. Despite decades of investigation, the nature of the association between thyroid disorders and cognition remains a mystery. Given the enhancing global burden of dementia, the principal purpose of this study was to elucidate the association between thyroid disturbances as a potentially modifiable risk factor of cognitive dysfunction. In this review study, we have tried to collect almost all of the reported mechanisms demonstrating the role of hypothyroidism and hyperthyroidism in the pathogenesis of dementia.

Assessment of Knowledge and Attitude Regarding Thyroid Disorders among Population in Taif City, Saudi Arabia

Background: Thyroid disorders are among the commonest endocrine disorders worldwide. Attention on people's knowledge and awareness about thyroid diseases is very important in helping for early diagnosis and early treatment of these disorders. The aim of this study to assess the degree of knowledge and attitude of thyroid gland and their disordersamong general population in Taif City, KSA. Methodology: A cross-sectional study was conducted on a representative sample of 600 Saudi adults of Taif general population. A pre-designed online questionnaire was used for data collection which consists of sociodemographic data, questions regarding knowledge and awareness of thyroid disorders. All data was entered and analyzed by using SPSS program version 22. Results: A total of 600 participants responded to the online questionnaire. Majority of respondents were aged between 18 to 32 years and males’ subjects were higher compared to the male counterparts (50.8%). Mean knowledge score of participants was 36.12. Participants who scored higher were 46.3% and considered as good knowledge level. 53.7% had bad knowledge level as they scored lower than mean score knowledge. Conclusion: Our study population show relatively good knowledge level compared to previous literature. Knowledge score was significantly associated with gender, educational level, working status and family income per month.

Thyroid Disorders and Diabetes Mellitus: Prevalence and Assosciation

Background: Diabetes mellitus and thyroid dysfunction are closely related. Numerous studies have reported an increased prevalence of thyroid disorders in diabetic patients, especially in type 1 diabetes mellitus. Objectives: Therefore, the purpose of this review is to discuss the numerous underlying mechanisms behind the relationship between diabetes mellitus and thyroid dysfunction in order to demonstrate that the correlation between these two prevalent conditions is unlikely to be a coincidental finding. Review: Diabetes and Thyroid disorders are characterized by endocrine system dysfunction. Thyroid hormones influence glucose metabolism in different ways, for example, they increase absorption of glucose from the gut, increase GLUT-2 level, regulate energy balance, and cause increased lipolysis which ultimately raises glucose levels in the body. Furthermore, thyroid hormones interact with adiponectin, leptin, ghrelin, to affect glucose metabolism. Additionally, studies suggest that hyperthyroidism impairs diabetic glycemic control, whereas hypothyroidism increases the risk of hypoglycemia, further complicating diabetes management. Conclusion: This paper emphasizes thyroid abnormalities, if left untreated, can raise the risk of several diabetes complications including retinopathy, neuropathy, and nephropathy, and can worsen diabetic symptoms. As a result, treating subclinical hypothyroidism or hypothyroidism in diabetic individuals can be advantageous. Therefore, a systematic method for early thyroid testing in diabetic patients to avoid severe complications is highly recommended.