Experimental Approaches Used to Examine Single Glutamate-Receptor Ion Channels in Locust Muscle Fibers

1983 ◽  
pp. 389-400 ◽  
Author(s):  
S. G. Cull-Candy ◽  
I. Parker
Keyword(s):  
Ion Channels ◽  
Glutamate Receptor ◽  
Muscle Fibers ◽  
Locust Muscle ◽  
Experimental Approaches

scholarly journals Role of Amino-Terminal Domain in the Assembly Mechanism of Kainate-Subtype Glutamate Receptor Ion Channels

2014 ◽  
Vol 106 (2) ◽  
pp. 151a
Author(s):  
Sagar Chittori ◽  
Janesh Kumar ◽  
Suvendu Lomash ◽  
Huaying Zhao ◽  
Peter Schuck ◽  
...  
Keyword(s):  
Ion Channels ◽  
Glutamate Receptor ◽  
Amino Terminal ◽  
Terminal Domain ◽  
Assembly Mechanism ◽  
Amino Terminal Domain

Glutamate Receptor-Like Ion Channels in Arabidopsis thaliana

2016 ◽  
pp. 69-81
Author(s):  
Hemant ◽  
Mohamed M. Ibrahim ◽  
Maryam Sarwat ◽  
Altaf Ahmad
Keyword(s):  
Arabidopsis Thaliana ◽  
Ion Channels ◽  
Glutamate Receptor

scholarly journals Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers

Channels ◽  
2012 ◽  
Vol 6 (4) ◽  
pp. 246-254 ◽  
Author(s):  
Tiffany C. Ho ◽  
Natalie A. Horn ◽  
Tuan Huynh ◽  
Lucy Kelava ◽  
Jeffry B. Lansman
Keyword(s):  
Skeletal Muscle ◽  
Ion Channels ◽  
Muscle Fibers ◽  
Mouse Skeletal Muscle ◽  
Mechanosensitive Ion Channels ◽  
Skeletal Muscle Fibers

Stretch-activated ion channels contribute to membrane depolarization after eccentric contractions

2000 ◽  
Vol 88 (1) ◽  
pp. 91-101 ◽  
Author(s):  
Todd A. McBride ◽  
Bradley W. Stockert ◽  
Fredric A. Gorin ◽  
Richard C. Carlsen
Keyword(s):  
Ion Channels ◽  
Channel Blocker ◽  
Contractile Function ◽  
Muscle Fibers ◽  
Membrane Depolarization ◽  
Membrane Potentials ◽  
Eccentric Contractions ◽  
Multiple Exposures ◽  
Cation Conductance ◽  
Stretch Activated Ion Channels

We tested the hypothesis that eccentric contractions activate mechanosensitive or stretch-activated ion channels (SAC) in skeletal muscles, producing increased cation conductance. Resting membrane potentials and contractile function were measured in rat tibialis anterior muscles after single or multiple exposures to a series of eccentric contractions. Each exposure produced a significant and prolonged (>24 h) membrane depolarization in exercised muscle fibers. The magnitude and duration of the depolarization were related to the number of contractions. Membrane depolarization was due primarily to an increase in Na+ influx, because the estimated Na+-to-K+ permeability ratio was increased in exercised muscles and resting membrane potentials could be partially repolarized by substituting an impermeant cation for extracellular Na+ concentration. Neither the Na+/H+ antiport inhibitor amiloride nor the fast Na+ channel blocker TTX had a significant effect on the depolarization. In contrast, addition of either of two nonselective SAC inhibitors, streptomycin or Gd3+, produced significant membrane repolarization. The results suggest that muscle fibers experience prolonged depolarization after eccentric contractions due, principally, to the activation of Na+-selective SAC.

scholarly journals Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

2021 ◽  
Vol 73 (4) ◽  
pp. 298-487
Author(s):  
Kasper B. Hansen ◽  
Lonnie P. Wollmuth ◽  
Derek Bowie ◽  
Hiro Furukawa ◽  
Frank S. Menniti ◽  
...  
Keyword(s):  
Ion Channels ◽  
Structure Function ◽  
Glutamate Receptor
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