scholarly journals Isolation and Culture of Neural Crest Stem Cells from Human Hair Follicles

2016 ◽  
pp. 49-55 ◽  
Author(s):  
Ruifeng Yang ◽  
Xiaowei Xu
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Human Hair ◽  
Hair Follicles ◽  
Neural Crest Stem Cells

scholarly journals BMP4-Induced Differentiation of Human Hair Follicle Neural Crest Stem Cells into Precursor Melanocytes from Hair Follicle Bulge

2020 ◽  
Vol 32 (5) ◽  
pp. 409
Author(s):  
Jung-Ho Yoon ◽  
Ho-Jin Kim ◽  
Jung-Hwan Kim ◽  
Tae-Hoon Kim ◽  
Chang-Hoon Seo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Hair Follicle ◽  
Human Hair ◽  
Human Hair Follicle ◽  
Induced Differentiation ◽  
Neural Crest Stem Cells

Neural crest stem cells from hair follicles and boundary cap have different effects on pancreatic isletsin vitro

2014 ◽  
Vol 125 (7) ◽  
pp. 547-554 ◽  
Author(s):  
Anastasiia Kosykh ◽  
Anongnad Ngamjariyawat ◽  
Svitlana Vasylovska ◽  
Niclas Konig ◽  
Carl Trolle ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Hair Follicles ◽  
Neural Crest Stem Cells

scholarly journals Gene profile of adult neural crest stem cells from hair follicles

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Yao Fei Hu ◽  
Maya Sieber‐Blum
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Hair Follicles ◽  
Gene Profile ◽  
Neural Crest Stem Cells

scholarly journals LARGE-SCALE EXPANSION AND CHARACTERIZATION OF HUMAN ADULT NEURAL CREST-DERIVED MULTIPOTENT STEM CELLS FROM HAIR FOLLICLE FOR REGENERATIVE MEDICINE APPLICATIONS

2017 ◽  
Vol 39 (3) ◽  
pp. 171-180 ◽  
Author(s):  
R G Vasyliev ◽  
A E Rodnichenko ◽  
O S Gubar ◽  
A V Zlatska ◽  
I M Gordiienko ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Hair Follicle ◽  
Human Hair ◽  
Large Scale ◽  
Hair Follicles ◽  
Human Hair Follicle ◽  
Self Renewal ◽  
Multipotent Stem Cells ◽  
Clonogenic Potential

Aim: The purpose of this work was to obtain, multiply and characterize the adult neural crest-derived multipotent stem cells from human hair follicle for their further clinical use. Materials and Methods: Adult neural crest-derived multipotent stem cells were obtained from human hair follicle by explant method and were expanded at large-scale up to a clinically significant number. The resulted cell cultures were examined by flow cytometry and immunocytochemical analysis. Their clonogenic potential, ability to self-renewal and directed multilineage differentiation were also investigated. Results: Cell cultures were obtained from explants of adult human hair follicles. Resulted cells according to morphological, phenotypic and functional criteria satisfied the definition of neural crest-derived multipotent stem cells. They had the phenotype Sox2+Sox10+Nestin+CD73+CD90+CD105+CD140a+CD 140b+CD146+CD166+CD271+CD349+ CD34-CD45-CD56-HLA-DR-, showed high clonogenic potential, ability to self-renewal and directed differentiation into the main derivatives of the neural crest: neurons, Schwann cells, adipocytes and osteoblasts. Conclusion: The possibility of a large-scale expansion of adult neural crest-derived multipotent stem cells up to 40–200·106 cells from minimal number of hair follicles with retention of their phenotype and functional properties are the significant step towards their translation into the clinical practice.

scholarly journals Corrigendum: BMP4-Induced Differentiation of Human Hair Follicle Neural Crest Stem Cells into Precursor Melanocytes from Hair Follicle Bulge

2020 ◽  
Vol 32 (6) ◽  
pp. 539
Author(s):  
Jung-Ho Yoon ◽  
Ho-Jin Kim ◽  
Jung-Hwan Kim ◽  
Tae-Hoon Kim ◽  
Chang-Hoon Seo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Hair Follicle ◽  
Human Hair ◽  
Human Hair Follicle ◽  
Induced Differentiation ◽  
Neural Crest Stem Cells
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