Characterization of Ligand Binding to GPCRs Through Computational Methods

Methods in Molecular Biology - Computational Methods for GPCR Drug Discovery ◽

10.1007/978-1-4939-7465-8_2 ◽

2017 ◽

pp. 23-44 ◽

Cited By ~ 3

Author(s):

Silvana Vasile ◽

Mauricio Esguerra ◽

Willem Jespers ◽

Ana Oliveira ◽

Jessica Sallander ◽

...

Keyword(s):

Ligand Binding ◽

Computational Methods

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Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain: Combining Experimental and Computational Methods Unravels Differences in Driving Forces

Journal of Chemical Information and Modeling ◽

10.1021/ci500559b ◽

2014 ◽

Vol 54 (12) ◽

pp. 3404-3416 ◽

Cited By ~ 14

Author(s):

Ann-Beth Nørholm ◽

Pierre Francotte ◽

Eric Goffin ◽

Iuliana Botez ◽

Laurence Danober ◽

...

Keyword(s):

Ligand Binding ◽

Glutamate Receptor ◽

Computational Methods ◽

Driving Forces ◽

Binding Domain ◽

Ligand Binding Domain ◽

Allosteric Modulators ◽

Thermodynamic Characterization ◽

Positive Allosteric Modulators

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Identification and Characterization of the Ligand Binding Subunit of a Kainic Acid Receptor Using Monoclonal Antibodies and Peptide Mapping

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)51632-x ◽

1989 ◽

Vol 264 (22) ◽

pp. 13329-13335

Author(s):

D R Hampson ◽

K D Wheaton ◽

C J Dechesne ◽

R J Wenthold

Keyword(s):

Monoclonal Antibodies ◽

Ligand Binding ◽

Kainic Acid ◽

Peptide Mapping ◽

Acid Receptor ◽

Identification And Characterization ◽

Binding Subunit

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Isolation and characterization of the two glycosylation isoforms of low molecular weight mannose 6-phosphate receptor from bovine testis. Effect of carbohydrate components on ligand binding.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)47417-6 ◽

1991 ◽

Vol 266 (26) ◽

pp. 17621-17630

Author(s):

M.M. Li ◽

G.W. Jourdian

Keyword(s):

Molecular Weight ◽

Ligand Binding ◽

Low Molecular Weight ◽

Isolation And Characterization ◽

Mannose 6 Phosphate ◽

Carbohydrate Components

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Odorant-binding protein. Characterization of ligand binding.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)39300-7 ◽

1990 ◽

Vol 265 (11) ◽

pp. 6118-6125

Author(s):

J Pevsner ◽

V Hou ◽

A M Snowman ◽

S H Snyder

Keyword(s):

Ligand Binding ◽

Binding Protein ◽

Protein Characterization ◽

Odorant Binding Protein ◽

Odorant Binding

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Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm501412a ◽

2014 ◽

Vol 57 (23) ◽

pp. 10072-10079 ◽

Cited By ~ 152

Author(s):

Mark E. Flanagan ◽

Joseph A. Abramite ◽

Dennis P. Anderson ◽

Ann Aulabaugh ◽

Upendra P. Dahal ◽

...

Keyword(s):

Computational Methods ◽

Prospective Design ◽

Irreversible Inhibitors ◽

Reactive Groups

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Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain

Oncogene ◽

10.1038/onc.2016.313 ◽

2016 ◽

Vol 36 (10) ◽

pp. 1440-1450 ◽

Cited By ~ 2

Author(s):

T Uo ◽

H Dvinge ◽

C C Sprenger ◽

R K Bradley ◽

P S Nelson ◽

...

Keyword(s):

Androgen Receptor ◽

Alternative Splicing ◽

Ligand Binding ◽

Functional Characterization ◽

Binding Domain ◽

Ligand Binding Domain ◽

Androgen Receptor Variants

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Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A/PUMA-G)

Molecular Pharmacology ◽

10.1124/mol.105.015750 ◽

2005 ◽

Vol 68 (5) ◽

pp. 1271-1280 ◽

Cited By ~ 80

Author(s):

Sorin Tunaru ◽

Jens Lättig ◽

Jukka Kero ◽

Gerd Krause ◽

Stefan Offermanns

Keyword(s):

Ligand Binding ◽

Nicotinic Acid ◽

Acid Receptor

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Characterization of labeled reagents in ligand-binding assays by a surface plasmon resonance biosensor

Bioanalysis ◽

10.4155/bio-2016-0204 ◽

2017 ◽

Vol 9 (2) ◽

pp. 193-207 ◽

Cited By ~ 5

Author(s):

Jia Duo ◽

JoAnne Bruno ◽

Steven Piccoli ◽

Binodh DeSilva ◽

Yan J Zhang

Keyword(s):

Surface Plasmon Resonance ◽

Ligand Binding ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Binding Assays ◽

Surface Plasmon Resonance Biosensor

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Tubulin and microtubules from bovine kidney: Purification, properties, and characterization of ligand binding

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(79)90303-5 ◽

1979 ◽

Vol 196 (2) ◽

pp. 511-524 ◽

Cited By ~ 22

Author(s):

Larry D. Barnes ◽

Glenda M. Roberson

Keyword(s):

Ligand Binding ◽

Bovine Kidney ◽

Properties And Characterization

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Characterization of ligand-binding systems by continuous affinity distributions of arbitrary shape

Analytical Biochemistry ◽

10.1016/0003-2697(80)90263-8 ◽

1980 ◽

Vol 103 (1) ◽

pp. 240-254 ◽

Cited By ~ 71

Author(s):

Ajit K. Thakur ◽

Peter J. Munson ◽

Donald L. Hunston ◽

David Rodbard

Keyword(s):

Ligand Binding ◽

Arbitrary Shape

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