“A CORRELATIONAL STUDY TO ASSESS THE KNOWLEDGE AND PRACTICE OF DIET ON PREMENSTRUAL SYNDROME AND OCCURRENCE OF PREMENSTRUAL SYNDROME AMONG ADOLESCENT GIRLS IN SELECTED COLLEGE”

Introduction: Premenstrual syndrome(PMS) is a group of symptoms that occur in women typically between ovulation and menstruation. The aim of the study was to evaluate the correlation between the knowledge and practice of diet on PMS and occurrence of PMS among adolescent girls. The objectives of the study were to assess the knowledge on diet of PMS among adolescent girls, to assess the practice on diet of PMS among adolescent girls, and to identify the occurrence of PMSamong adolescent girls, to correlate the practice on diet of PMS and occurrence of PMS among adolescent girls, to associate the knowledge scores on diet of PMS with selected socio - demographic variables. Methodology: The study was undertaken with 60 samples. Purposive sampling technique was used. The research design was correlation prospective design. Structured knowledge questionnaire and checklist were used for collecting the data. The data was analysed by using descriptive and inferential statistics. The study ndings show Result: ed that, among 60 samples , 37(62%) has poor knowledge,20(33%) have good knowledge and 3 (5%) has very good knowledge .At 0.05 level of signicance, the hypothesis (H ) was rejected 1 and(H )was accepted Hence it can be concluded that there is statistically signicant difference in the knowledge level of the adolescent girls 2 regarding the knowledge on practice of diet on PMS. The study outcome revealed that Conclusion: the practice of diet on PMS was moderately positive correlated with occurrence of PMS among adolescent girls

Longitudinal Analysis of Teacher Technology Acceptance and Its Relationship to Resource Viewing and Academic Performance of College Students during the COVID-19 Pandemic

Due to COVID-19, teachers quickly changed their courses from traditional face-to-face modality to emergency remote teaching (ERT), relying on learning management systems (LMS). In this simple prospective design study, we analyzed the relation of the level of teachers’ technological acceptance at the beginning of ERT (March 2020) considering three variables: the time spent by teachers in the LMS during that semester, the percentage of LMS’s resources their students viewed during the semester, and the final academic performance of the same students at the end of that semester (September 2020). This study included 251 teachers (57% male) and 12,185 students (45% male). We measured the teachers’ level of acceptance with the Spanish version of the Questionnaire Technology Acceptance Model (TAM). We found that the relation between the teacher’s acceptance and their time spent on the LMS was significant and positive (rho = 0.24, p < 0.001). In addition, teachers’ perception of LMS’s easiness is related to the percentage of educational resources their students utilized (rho = 0.26, p < 0.001). Finally, we found a relation between the usefulness dimension of the TAM to the academic performance of the students at the end of that semester (rho = 0.18, p < 0.01). Considering these results, we discuss practices for implementing quality education.

Sleep Reactivity and Depressive Symptoms Among Chinese Female Student Nurses: A Longitudinal Mediation Analysis

Previous cross-sectional studies have documented that sleep reactivity was associated with depressive symptoms, but the potential mechanisms underlying this relationship were understudied. Therefore, the present study with a longitudinal prospective design was to reveal the mediating roles of sleep disturbance and emotion regulation difficulties (ERD) between sleep reactivity and depressive symptoms. This study included 725 student nurses who were followed up periodically for 9 months, with an interval of three months. All participants completed questionnaires regarding sleep reactivity, sleep disturbance, ERD, and depressive symptoms. Adjusted analyses suggested that the direct effect of sleep reactivity on depressive symptoms was non-significant. The bootstrap procedure revealed two significant indirect effects: from sleep reactivity to depressive symptoms with sleep disturbance as a mediator and from sleep reactivity to depressive symptoms with sleep disturbance and ERD as sequential mediators. Therefore, sleep reactivity might be considered as an indicator of shiftwork adaptability in the evaluation of recruitment. Psychological interventions aimed at developing healthy sleep habits and emotion regulation skills may be helpful in decreasing the risk of depression.

Developmental and Etiological Patterns of Substance Use from Adolescence to Middle Age: A Longitudinal Twin Study

Background: Common liability to addiction framework suggests the tendency to use substances is largely a general heritable liability, but little is known about how expression of this liability varies from adolescence to middle age. We evaluated average trajectories of development and covariation underlying commonly used substances using a genetically informative prospective design spanning three decades. Methods: Using a sample of 3,762 twins across 7 prospective waves of assessment spanning ages 14-40, we modeled these relationships using two complementary approaches: common factor modeling and piecewise latent growth modeling with measures of alcohol, tobacco, and marijuana useResults: We found phenotypic (rp ~.3-.9) and genetic covariation (rg ~.3-1) between a single common factor at each age, though the factor explained less shared variance over time. Average substance use increased across adolescence for all phenotypes and either declined in adulthood or remained stable; these trajectories were heritable (~.35-.75) across all stages of development. We also found shared environmental covariation underlying growth model intercepts reflecting use at age 16 (rc ~.7-1). Conclusions: A heritable common factor accounted for co-occurring substance use from mid-adolescence to mid-adulthood, and greater substance specificity emerged with maturation. Similarly, all stages of substance use development were heritable, but correlations between substances weakened across development. These results extend and reinforce prior work examining consumption and problem use, providing new evidence over a broad age range showing that individuals use substances more indiscriminately at younger ages and show preferences later.

vHIT Testing of Vertical Semicircular Canals With Goggles Yield Different Results Depending on Which Canal Plane Being Tested

Objective: The use of goggles to assess vertical semicircular canal function has become a standard method in vestibular testing, both in clinic and in research, but there are different methods and apparatus in use. The aim of this study was to determine what the cause of the systematic differences is between gain values in testing of the vertical semicircular canals with two different video head impulse test (vHIT) equipment in subjects with normal vestibular function.Study Design: Retrospective analysis of gain values on patients with clinically deemed normal vestibular function (absence of a corrective eye saccade), tested with either Interacoustics or Otometrics system. Prospective testing of subjects with normal vestibular function with the camera records the eye movements of both eyes. Finally, 3D sensors were placed on different positions on the goggles measuring the actual vertical movement in the different semicircular planes.Results: In the clinical cohorts, the gain depended on which side and semicircular canal was tested (p &lt; 0.001). In the prospective design, the combination between the stimulated side, semicircular canal, and position of the recording device (right/left eye) highly influenced the derived gain (p &lt; 0.001). The different parts of the goggles also moved differently in a vertical direction during vertical semicircular canal testing.Conclusion: The gain values when testing the function of the vertical semicircular canals seem to depend upon which eye is recorded and which semicircular plane is tested and suggests caution when interpreting and comparing results when different systems are used both clinically as well as in research. The results also imply that further research and development are needed to obtain accurate vertical semicircular canal testing, in regard to both methodology and equipment design.

Effects of Oxygen via High-Flow Nasal Cannula on Adult Oropharyngeal Swallowing: A Literature Review

Purpose The use of high-flow oxygen via nasal cannula has become increasingly more common in various patient populations given the multiple benefits for treating respiratory distress and failure. There is emerging, though varying research on the impact high-flow oxygen delivery may have on adult oropharyngeal swallowing function. The purpose of this literature review is to outline available research and examine study design, populations investigated, findings, and clinical considerations of these findings. Method After an extensive online database search, we found five available peer-reviewed research articles specifically investigating oropharyngeal swallowing function in adults receiving high-flow nasal cannula (HFNC) therapy. Each article was reviewed and summarized in detail with close attention paid to results and clinical implications. Limitations, indirectness, and/or methodologic flaws are highlighted for the readers' consideration. Conclusions Four prospective design studies and one retrospective data analysis collection have been published evaluating the effects of high-flow oxygen therapy on adult oropharyngeal swallowing. Three of the prospective design studies evaluated healthy adults; one prospective design and the retrospective analysis data collection investigated acute care patients requiring HFNC. Study findings varied greatly likely due to variability of each study's subject population, design, and methods. Variability of results may make it challenging for speech pathologists attempting to use evidence-based decision making in clinical practice. Additional studies investigating nonhealthy subjects undergoing instrumental swallow studies while on HFNC are warranted.

An online GPCR structure analysis platform

We present an online, interactive platform for comparative analysis of all available G protein-coupled receptor structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied research studies.

Effects of a Comprehensive Pulmonary Rehabilitation in Severe Post-COVID-19 Patients

Background: Severe COVID-19 infection often leads to impairments requiring pulmonary rehabilitation (PR) following the acute phase. Little is known about the efficacy of PR in these patients. We therefore compared post-COVID-19 patients (PG) referred to PR patients with other lung diseases (LG). Methods: 99 PG were admitted to PR. In a prospective design, the results of PG were collected and compared to the results of LG of 2019 (n = 419) according to Functional Independence Measurement (FIM), Cumulative Illness Rating Scale (CIRS), 6-min walk test (6-MWT), duration of PR, and Feeling Thermometer (FT). Results: According to age, sex, and CIRS, both groups showed no significant differences. The improvements in the 6-MWT in the pre to post comparison were on average 180 (±101) meters for PG and 102 (±89) meters for LG (p < 0.001). FT showed a significant enhancement for PG of 21 (±14) points and for LG of 17 (±16) points (p < 0.039), while FIM significantly increased by 11 (±10) points in PG and 7 (±8) points in LG (p < 0.001). Conclusions: Comprehensive PR in PG is very effective according to the results in FIM, 6-MWT and FT. Therefore, we recommend PR following severe post-COVID-19 infections.

Incidence and risk factors of surgical site infection following colorectal surgery in Iran: a prospective cohort study

Background Surgical site infection (SSI) after colorectal surgery remains a significant problem for its negative clinical outcomes. The aim of this study was to determine the incidence of SSI after colorectal surgery in 5-Azar hospital of Gorgan, Golestan province, Iran and to further evaluate the related risk factors. Methods A prospective design was applied. Patients in the 5-Azar hospital of Gorgan, Golestan province, Iran was prospectively monitored for SSI after colorectal surgery. The demographic and perioperative characteristics were collected, and the main outcome were SSI within postoperative 30 days. Univariate analyses were used to identify risk factors. Results A total of 240 patients were enrolled in the study and the overall SSI rate was 23.3% (56 patients). Univariate analyses indicated that corticosteroids use (Risk Ratio (RR) = 3, 95% CI: 1.62–5.54), segmental resection with anastomosis (RR = 2.28, 95% CI: 1.12–4.63), anemia (RR = 4.52, 95% CI: 3.11–6.59), diabetics (RR = 2.68, 95% CI: 1.73–4.14), and opium use (RR = 1.87, 95% CI: 1.17–2.99) are risk factors for SSI. Conclusions SSI still seems to be a problem in colon surgery despite the observance of scientific principles. There are some risk factors for SSI that can be prevented.