positive allosteric modulators
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scholarly journals Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase

iScience ◽  
2021 ◽  
pp. 103650
Author(s):  
Evgeny Shlevkov ◽  
Param Murugan ◽  
Dan Montagna ◽  
Eric Stefan ◽  
Adelajda Hadzipasic ◽  
...  
Keyword(s):  
Small Molecule ◽  
E3 Ligase ◽  
Allosteric Modulators ◽  
Positive Allosteric Modulators

P.0229 Characterization of positive allosteric modulators of trkb for the treatment of depression

2021 ◽  
Vol 53 ◽  
pp. S166-S167
Author(s):  
J. Sandin ◽  
G. Nordvall ◽  
M. Dahlström ◽  
C. Parrado ◽  
M. Backlund ◽  
...  
Keyword(s):  
Allosteric Modulators ◽  
Treatment Of Depression ◽  
Positive Allosteric Modulators

scholarly journals De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects (Adv. Sci. 17/2021)

2021 ◽  
Vol 8 (17) ◽  
pp. 2170104
Author(s):  
Lizhen Xu ◽  
Heng Zhang ◽  
Yunfei Wang ◽  
Xiancui Lu ◽  
Zhenye Zhao ◽  
...  
Keyword(s):  
De Novo ◽  
De Novo Design ◽  
Allosteric Modulators ◽  
Analgesic Effects ◽  
Positive Allosteric Modulators

scholarly journals Scaffold Hopping to Imidazo[1,2-a]pyrazin-8-one Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptor

ACS Omega ◽  
2021 ◽  
Author(s):  
Ana I. de Lucas ◽  
Juan A. Vega ◽  
Aránzazu García Molina ◽  
María Lourdes Linares ◽  
Gary Tresadern ◽  
...  
Keyword(s):  
Allosteric Modulators ◽  
Scaffold Hopping ◽  
Metabotropic Glutamate ◽  
Positive Allosteric Modulators
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