Cell Transplantation for Spinal Cord Injury Repair

2000 ◽  
pp. 195-213 ◽  
Author(s):  
Juan C. Bartolomei ◽  
Charles A. Greer
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Injury Repair ◽  
Cord Injury

Optimizing Olfactory Ensheathing Cell Transplantation for Spinal Cord Injury Repair

2020 ◽  
Vol 37 (5) ◽  
pp. 817-829 ◽  
Author(s):  
Aaron D. Gilmour ◽  
Ronak Reshamwala ◽  
Alison A. Wright ◽  
Jenny A.K. Ekberg ◽  
James A. St John
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Olfactory Ensheathing Cell ◽  
Injury Repair ◽  
Cord Injury

scholarly journals Propofol promotes spinal cord injury repair by bone marrow mesenchymal stem cell transplantation

2015 ◽  
Vol 10 (8) ◽  
pp. 1305 ◽  
Author(s):  
Shu-bo Chen ◽  
Ya-jing Zhou ◽  
Jian-min Liu ◽  
Shu-ming Wei ◽  
Yun-hao Zhang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Mesenchymal Stem Cell Transplantation ◽  
Injury Repair ◽  
Cord Injury

Stem Cell Transplantation: A Promising Therapy for Spinal Cord Injury

2020 ◽  
Vol 15 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Zhe Gong ◽  
Kaishun Xia ◽  
Ankai Xu ◽  
Chao Yu ◽  
Chenggui Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Therapeutic Potential ◽  
Embryonic Stem ◽  
Current Status ◽  
Cord Injury

Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The incidence of SCI keeps increasing, resulting in huge burden on the society. The pathogenesis of SCI involves neuron death and exotic reaction, which could impede neuron regeneration. In clinic, the limited regenerative capacity of endogenous cells after SCI is a major problem. Recent studies have demonstrated that a variety of stem cells such as induced Pluripotent Stem Cells (iPSCs), Embryonic Stem Cells (ESCs), Mesenchymal Stem Cells (MSCs) and Neural Progenitor Cells (NPCs) /Neural Stem Cells (NSCs) have therapeutic potential for SCI. However, the efficacy and safety of these stem cellbased therapy for SCI remain controversial. In this review, we introduce the pathogenesis of SCI, summarize the current status of the application of these stem cells in SCI repair, and discuss possible mechanisms responsible for functional recovery of SCI after stem cell transplantation. Finally, we highlight several areas for further exploitation of stem cells as a promising regenerative therapy of SCI.

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