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Pharmacodynamic Measurements and Predictors of Response to Thymidylate Synthase Inhibitors
Antifolate Drugs in Cancer Therapy
◽
10.1007/978-1-59259-725-3_18
◽
1999
◽
pp. 383-396
Author(s):
David Farrugia
◽
Patrick G. Johnston
Keyword(s):
Thymidylate Synthase
◽
Predictors Of Response
◽
Thymidylate Synthase Inhibitors
Download Full-text
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References
Thymidylate synthase inhibitors: The in vitro activity of a series of heterocyclic benzoyl ring modified 2-desamino-2-methyl-N10-substituted-5,8-dideazafolates
Advances in Enzyme Regulation
◽
10.1016/0065-2571(91)90006-8
◽
1991
◽
Vol 31
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pp. 13-27
◽
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Author(s):
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...
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Thymidylate Synthase
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Vitro Activity
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In Vitro Activity
◽
Thymidylate Synthase Inhibitors
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Thymidylate synthase inhibitors as anticancer agents: from bench to bedside
Cancer Chemotherapy and Pharmacology
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10.1007/s00280-003-0625-9
◽
2003
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◽
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Author(s):
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◽
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Thymidylate Synthase
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Anticancer Agents
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Thymidylate Synthase Inhibitors
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Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells
Bioorganic & Medicinal Chemistry
◽
10.1016/j.bmc.2021.116136
◽
2021
◽
pp. 116136
Author(s):
Mohammad Mahboob Alam
◽
Azizah M. Malebari
◽
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◽
Thikryat Neamatallah
◽
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◽
...
Keyword(s):
Breast Cancer
◽
Molecular Docking
◽
Cancer Cells
◽
Thymidylate Synthase
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Breast Cancer Cells
◽
Docking Studies
◽
Design Synthesis
◽
Molecular Docking Studies
◽
Thymidylate Synthase Inhibitors
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Mechanisms of Acquired Resistance to Thymidylate Synthase Inhibitors: The Role of Enzyme Stability
Molecular Pharmacology
◽
10.1124/mol.56.5.1063
◽
1999
◽
Vol 56
(5)
◽
pp. 1063-1070
◽
Cited By ~ 35
Author(s):
Maria E. Kitchens
◽
Antonia M. Forsthoefel
◽
Karen W. Barbour
◽
H. Trent Spencer
◽
Franklin G. Berger
Keyword(s):
Thymidylate Synthase
◽
Enzyme Stability
◽
Acquired Resistance
◽
Thymidylate Synthase Inhibitors
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Folate-based thymidylate synthase inhibitors in cancer chemotherapy
Anti-Cancer Drugs
◽
10.1097/00001813-199701000-00001
◽
1997
◽
Vol 8
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◽
pp. 3-16
◽
Cited By ~ 43
Author(s):
Yuzuru Takemura
◽
Ann L. Jackman
Keyword(s):
Cancer Chemotherapy
◽
Thymidylate Synthase
◽
Thymidylate Synthase Inhibitors
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Role of P53 Status on Sensitivity to Thymidylate Synthase Inhibitors and Induction of Apoptosis
Chemistry and Biology of Pteridines and Folates
◽
10.1007/978-1-4615-0945-5_73
◽
2002
◽
pp. 433-437
Author(s):
H. H. J. Backus
◽
H. M. Pinedo
◽
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◽
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◽
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Thymidylate Synthase
◽
P53 Status
◽
Induction Of Apoptosis
◽
Thymidylate Synthase Inhibitors
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Molecular docking studies on quinazoline antifolate derivatives as human thymidylate synthase inhibitors
Bioinformation
◽
10.6026/97320630004357
◽
2010
◽
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◽
pp. 357-365
◽
Cited By ~ 4
Author(s):
V. Srivastava
◽
S.P. Gupta
◽
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◽
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Keyword(s):
Molecular Docking
◽
Thymidylate Synthase
◽
Docking Studies
◽
Molecular Docking Studies
◽
Thymidylate Synthase Inhibitors
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Use of Murine L5178Y Lymphoma Thymidine Kinase Mutants for in Vitro and in Vivo Antitumour Efficacy Evaluation of Novel Thymidylate Synthase Inhibitors
Advances in Experimental Medicine and Biology - Chemistry and Biology of Pteridines and Folates
◽
10.1007/978-1-4615-2960-6_120
◽
1993
◽
pp. 589-592
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◽
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Thymidylate Synthase Inhibitors
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Thymidylate synthase inhibitors
Cancer Chemotherapy and Biological Response Modifiers Annual
◽
10.1016/s0921-4410(03)21001-2
◽
2003
◽
pp. 1-28
◽
Cited By ~ 1
Author(s):
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◽
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◽
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Keyword(s):
Thymidylate Synthase
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Thymidylate Synthase Inhibitors
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Drugging Protein-Protein Interfaces of a Supramolecular Assembly as a Means to Overcome Resistance to Active Site Thymidylate Synthase Inhibitors
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◽
10.1016/j.bpj.2019.11.2836
◽
2020
◽
Vol 118
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◽
pp. 515a
Author(s):
Tigran M. Abramyan
◽
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◽
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◽
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Thymidylate Synthase
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Active Site
◽
Supramolecular Assembly
◽
Protein Interfaces
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Thymidylate Synthase Inhibitors
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