Generation of Antibodies That Are Externally Acting Isoform-Specific Inhibitors of Ion Channels

Author(s):  
Jacqueline Naylor ◽  
David J. Beech
2001 ◽  
Vol 28 (5-6) ◽  
pp. 451-458 ◽  
Author(s):  
Debra Patten ◽  
Graham R Foxon ◽  
Keith F Martin ◽  
Robert F Halliwell

1997 ◽  
Vol 100 (3) ◽  
pp. 481-490 ◽  
Author(s):  
Michael R. Blatt ◽  
Alexander Grabov

2006 ◽  
pp. S100-S101
Author(s):  
S P H Alexander ◽  
A Mathie ◽  
J A Peters

2015 ◽  
Vol 53 (08) ◽  
Author(s):  
A Shcherbokova ◽  
H Abdel-Aziz ◽  
O Kelber ◽  
K Nieber ◽  
G Ulrich-Merzenich

1974 ◽  
Vol 31 (03) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Cartwright

SummaryA method is described for the extraction with buffers of near physiological pH of a plasminogen activator from porcine salivary glands. Substantial purification of the activator was achieved although this was to some extent complicated by concomitant extraction of nucleic acid from the glands. Preliminary characterization experiments using specific inhibitors suggested that the activator functioned by a similar mechanism to that proposed for urokinase, but with some important kinetic differences in two-stage assay systems. The lack of reactivity of the pig gland enzyme in these systems might be related to the tendency to protein-protein interactions observed with this material.


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