Improving Nuclei/Gland Instance Segmentation in Histopathology Images by Full Resolution Neural Network and Spatial Constrained Loss

Author(s):  
Hui Qu ◽  
Zhennan Yan ◽  
Gregory M. Riedlinger ◽  
Subhajyoti De ◽  
Dimitris N. Metaxas
Author(s):  
Zhiyong Gao ◽  
Jianhong Xiang

Background: While detecting the object directly from the 3D point cloud, the natural 3D patterns and invariance of 3D data are often obscure. Objective: In this work, we aimed at studying the 3D object detection from discrete, disordered and sparse 3D point clouds. Methods: The CNN is composed of the frustum sequence module, 3D instance segmentation module S-NET, 3D point cloud transformation module T-NET, and 3D boundary box estimation module E-NET. The search space of the object is determined by the frustum sequence module. The instance segmentation of the point cloud is performed by the 3D instance segmentation module. The 3D coordinates of the object are confirmed by the transformation module and the 3D bounding box estimation module. Results: Evaluated on KITTI benchmark dataset, our method outperforms the state of the art by remarkable margins while having real-time capability. Conclusion: We achieve real-time 3D object detection by proposing an improved convolutional neural network (CNN) based on image-driven point clouds.


2020 ◽  
Vol 12 (20) ◽  
pp. 3274
Author(s):  
Keke Geng ◽  
Ge Dong ◽  
Guodong Yin ◽  
Jingyu Hu

Recent advancements in environmental perception for autonomous vehicles have been driven by deep learning-based approaches. However, effective traffic target detection in complex environments remains a challenging task. This paper presents a novel dual-modal instance segmentation deep neural network (DM-ISDNN) by merging camera and LIDAR data, which can be used to deal with the problem of target detection in complex environments efficiently based on multi-sensor data fusion. Due to the sparseness of the LIDAR point cloud data, we propose a weight assignment function that assigns different weight coefficients to different feature pyramid convolutional layers for the LIDAR sub-network. We compare and analyze the adaptations of early-, middle-, and late-stage fusion architectures in depth. By comprehensively considering the detection accuracy and detection speed, the middle-stage fusion architecture with a weight assignment mechanism, with the best performance, is selected. This work has great significance for exploring the best feature fusion scheme of a multi-modal neural network. In addition, we apply a mask distribution function to improve the quality of the predicted mask. A dual-modal traffic object instance segmentation dataset is established using a 7481 camera and LIDAR data pairs from the KITTI dataset, with 79,118 manually annotated instance masks. To the best of our knowledge, there is no existing instance annotation for the KITTI dataset with such quality and volume. A novel dual-modal dataset, composed of 14,652 camera and LIDAR data pairs, is collected using our own developed autonomous vehicle under different environmental conditions in real driving scenarios, for which a total of 62,579 instance masks are obtained using semi-automatic annotation method. This dataset can be used to validate the detection performance under complex environmental conditions of instance segmentation networks. Experimental results on the dual-modal KITTI Benchmark demonstrate that DM-ISDNN using middle-stage data fusion and the weight assignment mechanism has better detection performance than single- and dual-modal networks with other data fusion strategies, which validates the robustness and effectiveness of the proposed method. Meanwhile, compared to the state-of-the-art instance segmentation networks, our method shows much better detection performance, in terms of AP and F1 score, on the dual-modal dataset collected under complex environmental conditions, which further validates the superiority of our method.


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