Interventions for Refractory Pain in Cancer Patients

2020 ◽  
pp. 687-693
Author(s):  
Michael G. Kaplitt
Cureus ◽  
2019 ◽  
Author(s):  
Eduardo E Lovo ◽  
Fidel Campos ◽  
Victor E Caceros ◽  
Mario Minervini ◽  
Claudia B Cruz ◽  
...  

2009 ◽  
Vol 37 (1) ◽  
pp. 85-93 ◽  
Author(s):  
Shekhar Sharma ◽  
M.R. Rajagopal ◽  
Gayatri Palat ◽  
Charu Singh ◽  
Altaf G. Haji ◽  
...  

2020 ◽  
Vol 11 ◽  
pp. 72 ◽  
Author(s):  
Zaid Aljuboori ◽  
William Burke ◽  
Kimberly Meyer ◽  
Brian Williams

Background: Cancer pain can be debilitating and 10–20% of patients will have refractory pain despite optimal medical management. Here, we present a cost comparison of treating terminal cancer patients with intravenous (IV) narcotics, anterolateral cordotomy, or intrathecal pain pump (ITPP) placement. Case Description: We evaluated and treated 2 patients with metastatic breast cancer and expected survivals of <1 year. The first patient, a 53-year-old female, had tumor invasion of the right chest wall and had failed oral pain regimens; she was admitted to receive IV Dilaudid as patient-controlled analgesia (PCA). After 7 days of treatment without improvement, she underwent a left-sided C1-2 cordotomy. For her, the cost of the cordotomy was $18,462 and the expenses for 7 days hospital stay with PCA was $89,884; the total was $108,346. The second patient, a 60-year-old female, had severe somatic pain due to invasion by tumor of the left knee cap. She, too, has failed oral therapy and was receiving in-hospital IV Dilaudid PCA. Following 2 days of failed treatment, a morphine ITPP was placed and effectively treated her pain. In patient 2, the cost of the ITPP was $80,603 and the expenses for 8 days of the hospital stay with PCA came to $84,785; the total was $165,389. Conclusion: The treatment of refractory pain in cancer patients is challenging. It requires invasive procedures such as cordotomy or ITPP. Although procedures may yield comparable pain control, there was a significant cost savings for cordotomy versus ITPP ($57,043 saved).


2013 ◽  
Vol 16 (11) ◽  
pp. 1382-1387 ◽  
Author(s):  
Wadih Rhondali ◽  
Flora Tremellat ◽  
Mathilde Ledoux ◽  
Jean-François Ciais ◽  
Eduardo Bruera ◽  
...  

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Chang Sun ◽  
Yu-Tong Wang ◽  
Yu-Jie Dai ◽  
Zhi-Hui Liu ◽  
Jing Yang ◽  
...  

Background: The cisterna Intrathecal Drug Delivery system (IDDS) with morphine has proven to be effective in treating refractory cancer pain above the middle thoracic vertebrae level in some countries. However, it has not been fully investigated in others. We designed the current project to investigate the efficacy and safety of cisterna IDDS for pain relief in refractory pain above the middle thoracic vertebrae level in advanced cancer patients. Methods: This study protocol allows for eligible cancer patients to receive the cisterna IDDS operation. Pain intensity (Visual Analogue scale, VAS), quality of life (36-Item Short-Form Health Survey, SF-36), and depression (Self-Rating Depression scale, SDS) are assessed along with side effects in the postoperative follow-up visits. Recent literature suggests a potential role for cisterna IDDS morphine delivery for refractory pain states above the middle thoracic level. Conclusion: The results of this study may provide further evidence that cisterna IDDS of morphine can serve as an effective and safe pain relief strategy for refractory pain above the middle thoracic vertebrae level in advanced cancer patients.


2016 ◽  
Vol 63 (7) ◽  
pp. 1168-1174 ◽  
Author(s):  
Kathleen Gibbons ◽  
Andrea DeMonbrun ◽  
Elizabeth J. Beckman ◽  
Patricia Keefer ◽  
Deb Wagner ◽  
...  

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