Acquired Bleeding Disorders in Pregnancy: Obstetric Hemorrhage

Author(s):  
Sathana Ponnampalam ◽  
Sasha Wilson ◽  
Asma Khalil
2003 ◽  
Vol 13 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Jane Strong

Author(s):  
Sapna Ladani ◽  
Beverley J. Hunt ◽  
Sue Pavord

This chapter aims to cover aspects of haematology of pregnancy, delivery, and postpartum that are not addressed in other chapters. Obstetric haematology is a vast and complex area, the importance of which has promoted the development of this as a unique subspecialty. Thrombosis and bleeding, anaemia, haemoglobinopathies, and microangiopathies still account for significant morbidity and mortality in pregnancy, despite improvements in recognition, prevention, and management. Anaemia, due to iron deficiency, is highly prevalent in the pregnant population, but with early recognition and treatment, morbidity and need for unnecessary blood transfusion can be avoided. The management of women with thrombocytopenias and inherited bleeding disorders can be complex because of the haemostatic challenges of pregnancy. Pregnancies in women with haematological disorders need to be carefully managed to reduce mortality and morbidity in the mother and fetus. This chapter addresses the management of anaemia, haemoglobinopathies (mainly sickle cell disease), thrombocytopenia, microangiopathies, and the inherited bleeding disorders.


2008 ◽  
Vol 18 (8) ◽  
pp. 217-223 ◽  
Author(s):  
Elefheria Lefkou ◽  
Beverley J. Hunt

Hematology ◽  
2016 ◽  
Vol 2016 (1) ◽  
pp. 232-235 ◽  
Author(s):  
Terry B. Gernsheimer

Abstract Obstetrical hematology represents challenges not only for the patient, but also for her progeny. In particular, bleeding disorders, both congenital and acquired, not only present problems both for delivery and in the immediate postpartum period, but also may have significant implications for the fetus and neonate. Women with congenital bleeding disorders or who are carriers of X-linked or autosomal disorders should be counseled prior to conception so that pregnancy can be safely undertaken with careful preparation. A treatment plan should be set up by a specialized care team that includes the hematologist, obstetrician, and anesthesiologist; the patient should be followed closely during pregnancy, through delivery, and in the immediate postpartum period. Acquired disorders of hemostasis that occur with pregnancy may present particular diagnostic difficulties and require rapid diagnosis and management.


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