scholarly journals Therapeutic Nuclear Medicine in the UK

Author(s):  
John Buscombe
2019 ◽  
Vol 107 (9-11) ◽  
pp. 1087-1120 ◽  
Author(s):  
Nkemakonam C. Okoye ◽  
Jakob E. Baumeister ◽  
Firouzeh Najafi Khosroshahi ◽  
Heather M. Hennkens ◽  
Silvia S. Jurisson

Abstract Diagnostic and therapeutic nuclear medicine relies heavily on radiometal nuclides. The most widely used and well-known radionuclide is technetium-99m (99mTc), which has dominated diagnostic nuclear medicine since the advent of the 99Mo/99mTc generator in the 1960s. Since that time, many more radiometals have been developed and incorporated into potential radiopharmaceuticals. One critical aspect of radiometal-containing radiopharmaceuticals is their stability under in vivo conditions. The chelator that is coordinated to the radiometal is a key factor in determining radiometal complex stability. The chelators that have shown the most promise and are under investigation in the development of diagnostic and therapeutic radiopharmaceuticals over the last 5 years are discussed in this review.


2015 ◽  
Vol 43 (4) ◽  
pp. 800-803
Author(s):  
Brian Neilly ◽  
Sabina Dizdarevic ◽  
Liz Prvulovich ◽  
John Buscombe ◽  
Val Lewington

1989 ◽  
Vol 10 (3) ◽  
pp. 181-189 ◽  
Author(s):  
E. D. WILLIAMS ◽  
L. K. HARDING ◽  
J. H. McKILLOP

2003 ◽  
Vol 18 (1) ◽  
pp. 109-115 ◽  
Author(s):  
Isabelle Gardin ◽  
Lionel G. Bouchet ◽  
Karine Assié ◽  
Jerome Caron ◽  
Albert Lisbona ◽  
...  

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