Vitamin D and Fall Prevention: An Update

2016 ◽  
pp. 197-205 ◽  
Author(s):  
Heike A. Bischoff-Ferrari ◽  
Bess Dawson-Hughes
Keyword(s):  
Vitamin D ◽  
Fall Prevention

scholarly journals Effect of Vitamin D Supplementation on Falls, Physical Function, and Activity: Results From the STURDY Trial

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 758-759
Author(s):  
Jennifer Schrack ◽  
Lawrence Appel ◽  
Lewis Lipsitz
Keyword(s):  
Vitamin D ◽  
Fall Prevention ◽  
Gait Speed ◽  
Vitamin D Supplementation ◽  
Dose Finding ◽  
Secondary Outcome ◽  
Skeletal Muscle Function ◽  
Risk Of Falls ◽  
Objectively Measured ◽  
Minute Walk

Abstract Each year, 2.8 million older adults are treated for falls, with over 800,000 hospitalized. Evidence suggests vitamin D supplementation might reduce the risk of falls, potentially through improvements in skeletal muscle function; however, results are inconsistent. In 2013 the NIA issued a request for applications to assess the efficacy and dose-response of vitamin D supplementation for fall prevention across a range of doses and serum 25(OH)D concentrations, resulting in the funding of STURDY (Study To Understand Fall Reduction and Vitamin D in You). STURDY was a seamless dose-finding and confirmatory, double-masked, response adaptive Bayesian randomized trial designed to find the best dose of vitamin D supplementation for fall prevention. Participants (n=688, ≥70 years with serum 25(OH)D of 10-29 ng/mL) were randomized to 200 (control), 1000 , 2000, or 4000 IU/day of vitamin D3.The first participant was randomized on 10/30/2015 and data collection ended on 5/31/2019. The primary outcome was time to first fall or death, and the secondary outcome was gait speed. Dr. Appel will present the main findings of the effect of vitamin D supplementation on time to first fall. Dr. Wanigatunga will present a more detailed analysis of the effect of vitamin D supplementation on fall characteristics, including indoor vs. outdoor falls, consequential falls, and repeat fall risk. Dr. Guralnik will present the effect of vitamin D supplementation on physical functioning, including gait speed, SPPB, 6-minute walk, and TUG performance. Dr. Schrack will present the effect of vitamin D supplementation on objectively measured physical activity.

Relevance of vitamin D in fall prevention

2017 ◽  
Vol 15 (1) ◽  
pp. E1-E7
Author(s):  
Heike A. Bischoff-Ferrari
Keyword(s):  
Vitamin D ◽  
Fall Prevention

scholarly journals Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?

2006 ◽  
Vol 17 (5) ◽  
pp. 656-663 ◽  
Author(s):  
H. A. Bischoff-Ferrari ◽  
M. Conzelmann ◽  
H. B. Stähelin ◽  
W. Dick ◽  
M. G. Carpenter ◽  
...  
Keyword(s):  
Vitamin D ◽  
Fall Prevention ◽  
Dynamic Balance

scholarly journals Vitamin D supplementation as a fall prevention method: A systematic review

2020 ◽  
Vol 13 (4) ◽  
Author(s):  
Ibrahim Mahmoud Ajwah ◽  
Eid Muflih Albalawi ◽  
Ziyad Faraj Albalawi ◽  
Waad Mohammed Alhawiti ◽  
Nasser Faris Alahmari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Fall Prevention ◽  
Vitamin D Supplementation ◽  
Prevention Method

Vitamin D for Fall Prevention

2015 ◽  
Vol 16 (7) ◽  
pp. 10
Author(s):  
Neil Skolnik ◽  
Katie Bowry
Keyword(s):  
Vitamin D ◽  
Fall Prevention

Association Between Vitamin D Supplementation and Fall Prevention: A Pool Evaluation

2021 ◽  
Author(s):  
Fei-Long Wei ◽  
Tian Li ◽  
Yuli Huang ◽  
Cheng-Pei Zhou ◽  
Wen Wang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Fall Prevention ◽  
Vitamin D Supplementation

scholarly journals Fall prevention and vitamin D in the elderly: an overview of the key role of the non-bone effects

2010 ◽  
Vol 7 (1) ◽  
Author(s):  
Cedric Annweiler ◽  
Manuel Montero-Odasso ◽  
Anne M Schott ◽  
Gilles Berrut ◽  
Bruno Fantino ◽  
...  
Keyword(s):  
Vitamin D ◽  
Fall Prevention ◽  
The Elderly

scholarly journals Exercise and Vitamin D in Fall Prevention Among Older Women

2015 ◽  
Vol 175 (5) ◽  
pp. 703 ◽  
Author(s):  
Kirsti Uusi-Rasi ◽  
Radhika Patil ◽  
Saija Karinkanta ◽  
Pekka Kannus ◽  
Kari Tokola ◽  
...  
Keyword(s):  
Vitamin D ◽  
Older Women ◽  
Fall Prevention

Vitamin D Effects on Bone and Muscle

2011 ◽  
Vol 81 (4) ◽  
pp. 264-272 ◽  
Author(s):  
Heike Bischoff-Ferrari ◽  
Hannes B. Stähelin ◽  
Paul Walter
Keyword(s):  
Vitamin D ◽  
Fall Prevention ◽  
Cardiovascular Health ◽  
Data Transfer ◽  
Fracture Prevention ◽  
Institute Of Medicine ◽  
Lower Extremity Function ◽  
Common Chronic Disease ◽  
Hydroxyvitamin D ◽  
Prevention Of Cancer

Increasing data suggest that higher 25-hydroxyvitamin D [25(OH)D] serum concentrations are advantageous for health. At present, strong evidence for causality is available for fracture and fall prevention, while promising epidemiologic and mechanistic studies suggest a key role of vitamin D in the preservation of cardiovascular health, and the prevention of cancer and other common chronic disease. For lower extremity function, fall prevention, hip bone density, and for fracture prevention optimal benefits are observed with 25(OH)D levels of at least 75 nmol/L to 100 nmol/L [1]. This threshold may be reached in 50 % of adults with 800 to 1000 IU vitamin D per day. This manuscript will discuss the evidence of vitamin D in fall and fracture prevention and how these data transfer to the most recent recommendations by the IOF (International Osteoporosis Foundation) and the IOM (Institute of Medicine).

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