Human Protein Kinases and Obesity

2017 ◽  
pp. 111-134 ◽  
Author(s):  
Atilla Engin
Keyword(s):  
Protein Kinases ◽  
Human Protein

scholarly journals HomoKinase: A Curated Database of Human Protein Kinases

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Suresh Subramani ◽  
Saranya Jayapalan ◽  
Raja Kalpana ◽  
Jeyakumar Natarajan
Keyword(s):  
Gene Ontology ◽  
Protein Kinases ◽  
Kinase Activity ◽  
Query Protein ◽  
Amino Acid Sequences ◽  
Human Protein ◽  
Biological Information ◽  
Functional Domain ◽  
Comprehensive Collection ◽  
Search Tool

HomoKinase database is a comprehensive collection of curated human protein kinases and their relevant biological information. The entries in the database are curated by three criteria: HGNC approval, gene ontology-based biological process (protein phosphorylation), and molecular function (ATP binding and kinase activity). For a given query protein kinase name, the database provides its official symbol, full name, other known aliases, amino acid sequences, functional domain, gene ontology, pathways assignments, and drug compounds. In addition, as a search tool, it enables the retrieval of similar protein kinases with specific family, subfamily, group, and domain combinations and tabulates the information. The present version contains 498 curated human protein kinases and links to other popular databases.

scholarly journals wKinMut: An integrated tool for the analysis and interpretation of mutations in human protein kinases

2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Jose MG Izarzugaza ◽  
Miguel Vazquez ◽  
Angela del Pozo ◽  
Alfonso Valencia
Keyword(s):  
Protein Kinases ◽  
Human Protein

scholarly journals wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases

2015 ◽  
Vol 37 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Miguel Vazquez ◽  
Tirso Pons ◽  
Søren Brunak ◽  
Alfonso Valencia ◽  
Jose M.G. Izarzugaza
Keyword(s):  
Protein Kinases ◽  
Human Protein ◽  
Pathogenic Variants

Fragment-based structure-guided drug discovery: strategy, process, and lessons from human protein kinases

Drug Design ◽  
2010 ◽  
pp. 30-40 ◽  
Author(s):  
Stephen K. Burley ◽  
Gavin Hirst ◽  
Paul Sprengeler ◽  
Siegfried Reich
Keyword(s):  
Drug Discovery ◽  
Protein Kinases ◽  
Human Protein ◽  
Strategy Process

Search for Inhibitors of Bacterial and Human Protein Kinases among Derivatives of Diazepines[1,4] Annelated with Maleimide and Indole Cycles

2008 ◽  
Vol 51 (24) ◽  
pp. 7731-7736 ◽  
Author(s):  
Valery N. Danilenko ◽  
Alexander Y. Simonov ◽  
Sergey A. Lakatosh ◽  
Michael H. G. Kubbutat ◽  
Frank Totzke ◽  
...  
Keyword(s):  
Protein Kinases ◽  
Human Protein ◽  
Derivatives Of

Benzofuran Small Molecules as Potential Inhibitors of Human Protein Kinases. A Review

2016 ◽  
Vol 22 (7) ◽  
pp. 879-894 ◽  
Author(s):  
Halina Kwiecie| ◽  
Agata Goszczy|ska ◽  
Paulina Rokosz
Keyword(s):  
Small Molecules ◽  
Protein Kinases ◽  
Human Protein ◽  
Potential Inhibitors

scholarly journals Quantitative Site-specific Phosphorylation Dynamics of Human Protein Kinases during Mitotic Progression

2010 ◽  
Vol 9 (6) ◽  
pp. 1167-1181 ◽  
Author(s):  
Kalyan Dulla ◽  
Henrik Daub ◽  
Renate Hornberger ◽  
Erich A. Nigg ◽  
Roman Körner
Keyword(s):  
Protein Kinases ◽  
Human Protein ◽  
Mitotic Progression ◽  
Site Specific

scholarly journals Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies

RSC Advances ◽  
2017 ◽  
Vol 7 (65) ◽  
pp. 41265-41271 ◽  
Author(s):  
Dagmar Stumpfe ◽  
Annachiara Tinivella ◽  
Giulio Rastelli ◽  
Jürgen Bajorath
Keyword(s):  
Protein Kinases ◽  
Kinase Inhibitors ◽  
Human Protein ◽  
Confidence Levels ◽  
The One ◽  
The Right

Kinase inhibitors from screening data. Shown are two analogs that were tested against 10 (left) and 13 (right) different kinases. The inhibitor on the left was active against a single kinase and the one on the right against three kinases.

scholarly journals Characterization of pathogenic germline mutations in human Protein Kinases

2011 ◽  
Vol 12 (S4) ◽  
Author(s):  
Jose MG Izarzugaza ◽  
Lisa EM Hopcroft ◽  
Anja Baresic ◽  
Christine A Orengo ◽  
Andrew CR Martin ◽  
...  
Keyword(s):  
Protein Kinases ◽  
Germline Mutations ◽  
Human Protein
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