15th International Congress on Antiphospholipid Antibodies Task Force on Catastrophic Antiphospholipid Syndrome Report

The Task Force on Catastrophic Antiphospholipid Syndrome (CAPS) met again on occasion of the 16th International Congress on Antiphospholipid Antibodies (aPL) that was held in Manchester, England, in September 2019. Its aims were to assess the up-to-date knowledge on pathogenesis, clinical and laboratory features, diagnosis and classification, precipitating factors, and treatment of CAPS. This article summarizes the main aspects that were presented during the Task Force meeting at that Congress.

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14th International Congress on Antiphospholipid Antibodies Task Force Report on Catastrophic Antiphospholipid Syndrome

Autoimmunity Reviews ◽

10.1016/j.autrev.2014.03.002 ◽

2014 ◽

Vol 13 (7) ◽

pp. 699-707 ◽

Cited By ~ 125

Author(s):

Ricard Cervera ◽

Ignasi Rodríguez-Pintó ◽

Serena Colafrancesco ◽

Fabrizio Conti ◽

Guido Valesini ◽

...

Keyword(s):

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

International Congress ◽

Catastrophic Antiphospholipid Syndrome ◽

Task Force Report

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15th International Congress on Antiphospholipid Antibodies Task Force on Pediatric Antiphospholipid Syndrome Report

Antiphospholipid Syndrome ◽

10.1007/978-3-319-55442-6_16 ◽

2017 ◽

pp. 291-306

Author(s):

Arzu Soybilgic ◽

Cassyanne L. Aguiar ◽

M. Patricia Massicotte ◽

Gili Kenet ◽

E. Ann Yeh ◽

...

Keyword(s):

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

International Congress ◽

Syndrome Report

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Erratum to 16th international congress on antiphospholipid antibodies task force report on antiphospholipid syndrome treatment trends

Lupus ◽

10.1177/0961203320985066 ◽

2020 ◽

pp. 096120332098506

Keyword(s):

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

International Congress ◽

Task Force Report ◽

Treatment Trends

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15th International Congress on Antiphospholipid Antibodies Task Force on Antiphospholipid Syndrome Treatment Trends Report

Antiphospholipid Syndrome ◽

10.1007/978-3-319-55442-6_18 ◽

2017 ◽

pp. 317-338 ◽

Cited By ~ 12

Author(s):

Danieli Andrade ◽

Ricard Cervera ◽

Hannah Cohen ◽

Mark Crowther ◽

Maria J. Cuadrado ◽

...

Keyword(s):

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

International Congress ◽

Treatment Trends

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14th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends

Autoimmunity Reviews ◽

10.1016/j.autrev.2014.01.053 ◽

2014 ◽

Vol 13 (6) ◽

pp. 685-696 ◽

Cited By ~ 217

Author(s):

Doruk Erkan ◽

Cassyanne L. Aguiar ◽

Danieli Andrade ◽

Hannah Cohen ◽

Maria J. Cuadrado ◽

...

Keyword(s):

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

International Congress ◽

Task Force Report ◽

Treatment Trends

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The relevance of “non-criteria” clinical manifestations of antiphospholipid syndrome: 14th International Congress on Antiphospholipid Antibodies Technical Task Force Report on Antiphospholipid Syndrome Clinical Features

Autoimmunity Reviews ◽

10.1016/j.autrev.2015.01.002 ◽

2015 ◽

Vol 14 (5) ◽

pp. 401-414 ◽

Cited By ~ 107

Author(s):

Mirhelen M. Abreu ◽

Adriana Danowski ◽

Denis G. Wahl ◽

Mary-Carmen Amigo ◽

Maria Tektonidou ◽

...

Keyword(s):

Clinical Features ◽

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

Clinical Manifestations ◽

International Congress ◽

Task Force Report

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16th International congress on antiphospholipid antibodies task force report on clinical manifestations of antiphospholipid syndrome

Lupus ◽

10.1177/09612033211020361 ◽

2021 ◽

pp. 096120332110203

Author(s):

Savino Sciascia ◽

Massimo Radin ◽

Irene Cecchi ◽

Roger A Levy ◽

Doruk Erkan

Keyword(s):

Risk Stratification ◽

Antiphospholipid Syndrome ◽

Antiphospholipid Antibodies ◽

Task Force ◽

Current Knowledge ◽

Clinical Manifestations ◽

International Congress ◽

Level Of Evidence ◽

Task Force Report

The objectives of the 16th International Congress on Antiphospholipid Antibodies (aPL) Task Force on Clinical Manifestations of Antiphospholipid Syndrome (APS) were to critically analyze: a) the definition of “APS”; b) the current knowledge on non-traditional manifestations associated with aPL; and c) the risk stratification strategies in aPL-positive patients. The quality of evidence was assessed by the GRADE system. The task force concluded that: a) APS does not have a uniform definition given the heterogeneity of the clinical presentations and different aPL profiles; b) current literature supports the role for aPL testing in cases of thrombocytopenia and recurrent cardiac events but are limited by vast heterogeneity, providing an overall low-to-very low level of evidence; and c) risk stratification strategies in aPL-positive patients, such as aPL-Score and Global APS Score, can be useful in clinical practice. International multicenter studies are still highly needed to improve the quality of available evidence and consequently the strength of future recommendations.

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