Functional Behavior-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Behavior in Children with ASD

2021 ◽  
pp. 2114-2122
Author(s):  
Tricia Vause ◽  
Nicole Neil ◽  
Maurice Feldman
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Compulsive Behavior ◽  
Obsessive Compulsive ◽  
Functional Behavior ◽  
Children With Asd ◽  
Behavior Based ◽  
Obsessive Compulsive Behavior

scholarly journals NMDA receptors and fear extinction: implications for cognitive behavioral therapy

2011 ◽  
Vol 13 (4) ◽  
pp. 463-474 ◽  
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Nmda Receptors ◽  
Partial Agonist ◽  
Behavioral Therapy ◽  
Conditioned Fear ◽  
Fear Extinction ◽  
Cognitive Behavioral ◽  
Compulsive Behavior ◽  
Obsessive Compulsive ◽  
Fear Of Heights

Based primarily on studies that employ Pavlovian fear conditioning, extinction of conditioned fear has been found to be mediated by N-methyi-D-aspartate (NMDA) receptors in the amygdala and medial prefrontal cortex. This led to the discovery that an NMDA partial agonist, D-cycloserine, could facilitate fear extinction when given systemically or locally into the amygdala. Because many forms of cognitive behavioral therapy depend on fear extinction, this led to the successful use of D-cycloserine as an adjunct to psychotherapy in patients with so-called simple phobias (fear of heights), social phobia, obsessive-compulsive behavior, and panic disorder. Data in support of these conclusions are reviewed, along with some of the possible limitations of D-cycloserine as an adjunct to psychotherapy.

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