Hybrid Imaging for Tumours of the Chest

2019 ◽  
pp. 523-542
Author(s):  
Roberto C. Delgado Bolton ◽  
Adriana K. Calapaquí Terán
Keyword(s):  
Hybrid Imaging

Radionuclide hybrid imaging in common garden slugs (Arionidae)

2020 ◽  
Author(s):  
N Beindorff ◽  
D Messroghli ◽  
JF Eary ◽  
W Brenner
Keyword(s):  
Hybrid Imaging ◽  
Common Garden

scholarly journals Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT

2021 ◽  
Author(s):  
Stefan A. Koerber ◽  
R. Finck ◽  
K. Dendl ◽  
M. Uhl ◽  
T. Lindner ◽  
...  
Keyword(s):  
Hybrid Imaging ◽  
Background Activity ◽  
The Novel ◽  
Malignant Tissue ◽  
Primary Tumors ◽  
Aggressive Disease ◽  
Standardized Uptake Values ◽  
Pet Ct ◽  
Pet Scans

Abstract Purpose A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a first clinical evaluation. Methods A cohort of 15 patients underwent 68Ga-FAPI-PET/CT for staging or restaging. The acquisition of PET scans was performed 60 min after administration of 127 to 308 MBq of the tracer. The uptake of 68Ga-FAPI in malignant tissue as well as in healthy organs was quantified by standardized uptake values SUVmean and SUVmax. Results Excellent tumor-to-background ratios (> 7) could be achieved due to low background activity and high SUVmax in primary tumors (median 7.16), local relapses (median 11.47), and metastases (median 6.29). The highest uptake was found for liposarcomas and high-grade disease (range 18.86–33.61). A high SUVmax (> 10) was observed for clinically more aggressive disease. Conclusion These preliminary findings suggest a high potential for the clinical use of 68Ga-FAPI-PET/CT for patients diagnosed with sarcoma.

Whole-body hybrid imaging concept for the integration of PET/MR into radiation therapy treatment planning

2016 ◽  
Vol 61 (9) ◽  
pp. 3504-3520 ◽  
Author(s):  
Daniel H Paulus ◽  
Mark Oehmigen ◽  
Johannes Grueneisen ◽  
Lale Umutlu ◽  
Harald H Quick
Keyword(s):  
Radiation Therapy ◽  
Treatment Planning ◽  
Hybrid Imaging ◽  
Whole Body ◽  
Radiation Therapy Treatment Planning ◽  
Therapy Treatment

Parallel Optical Interconnections Using Surface-emitting Microlasers And A Hybrid Imaging System

2005 ◽  
Author(s):  
J. Jahns ◽  
F. Sauer ◽  
B. Tell ◽  
K.F. Brown-Goebeler ◽  
A.Y. Feldblum ◽  
...  
Keyword(s):  
Hybrid Imaging ◽  
Imaging System ◽  
Optical Interconnections ◽  
Hybrid Imaging System

scholarly journals Infrared vibrational nanocrystallography and nanoimaging

2016 ◽  
Vol 2 (10) ◽  
pp. e1601006 ◽  
Author(s):  
Eric A. Muller ◽  
Benjamin Pollard ◽  
Hans A. Bechtel ◽  
Peter van Blerkom ◽  
Markus B. Raschke
Keyword(s):  
Ion Mobility ◽  
Molecular Orientation ◽  
Hybrid Imaging ◽  
Defect Formation ◽  
Near Field ◽  
Molecular Solids ◽  
Optical Antenna ◽  
Molecular Bond ◽  
Low Symmetry ◽  
Insight Into

Molecular solids and polymers can form low-symmetry crystal structures that exhibit anisotropic electron and ion mobility in engineered devices or biological systems. The distribution of molecular orientation and disorder then controls the macroscopic material response, yet it is difficult to image with conventional techniques on the nanoscale. We demonstrated a new form of optical nanocrystallography that combines scattering-type scanning near-field optical microscopy with both optical antenna and tip-selective infrared vibrational spectroscopy. From the symmetry-selective probing of molecular bond orientation with nanometer spatial resolution, we determined crystalline phases and orientation in aggregates and films of the organic electronic material perylenetetracarboxylic dianhydride. Mapping disorder within and between individual nanoscale domains, the correlative hybrid imaging of nanoscale heterogeneity provides insight into defect formation and propagation during growth in functional molecular solids.

Comment on ‘extended depth of field in hybrid imaging systems: circular aperture’

2005 ◽  
Vol 52 (13) ◽  
pp. 1783-1788
Author(s):  
S. S. Sherif * ◽  
G. Muyo ◽  
A. R. Harvey
Keyword(s):  
Hybrid Imaging ◽  
Imaging Systems ◽  
Depth Of Field ◽  
Circular Aperture ◽  
Extended Depth Of Field

Towards improved hardware component attenuation correction in PET/MR hybrid imaging

2013 ◽  
Vol 58 (22) ◽  
pp. 8021-8040 ◽  
Author(s):  
D H Paulus ◽  
L Tellmann ◽  
H H Quick
Keyword(s):  
Attenuation Correction ◽  
Hybrid Imaging ◽  
Hardware Component

Hybrid Imaging System for Developing Novel Neural Contrast Agents

2007 ◽  
Author(s):  
Russell S. Witte ◽  
Sheng-Wen Huang ◽  
Shai Ashkenazi ◽  
Matthew O'Donnell
Keyword(s):  
Contrast Agents ◽  
Hybrid Imaging ◽  
Imaging System ◽  
Hybrid Imaging System

Hybrid coronary computed tomography angiography and positron emission tomography myocardial perfusion imaging in evaluation of recurrent symptoms after coronary artery bypass grafting

2018 ◽  
Vol 20 (11) ◽  
pp. 1298-1304 ◽  
Author(s):  
Teemu Maaniitty ◽  
Samuli Jaakkola ◽  
Antti Saraste ◽  
Juhani Knuuti
Keyword(s):  
Myocardial Perfusion ◽  
Perfusion Defect ◽  
Hybrid Imaging ◽  
Coronary Computed Tomography Angiography ◽  
Artery Bypass ◽  
Emission Tomography ◽  
Bypass Grafting ◽  
Bypass Grafts ◽  
Complementary Information ◽  
Positron Emission

Abstract Aims Recurrent chest pain after coronary artery bypass grafting (CABG) poses a diagnostic challenge. We hypothesized that combining anatomy of bypass grafts and native coronary arteries with ischaemia detection by hybrid imaging could be used to gain valuable and complementary information in patients with recurrent symptoms after CABG. Methods and results We analysed 36 consecutive patients (67 ± 9 years, 81% male) who had undergone hybrid imaging using coronary computed tomography angiography (CCTA) and [15O]H2O positron emission tomography (PET) myocardial perfusion imaging due to recurrent symptoms after CABG. Coronary tree and left ventricular myocardium were divided into three main territories, yielding a total of 108 coronary territories in 36 patients. The presence of obstructive (≥50%) stenosis and the patency of grafts were evaluated by CCTA, while myocardial ischaemia was assessed by quantitative adenosine-stress PET. Altogether 28 (78%) of the 36 study patients presented with matched PET/CCTA abnormalities. Forty-one coronary territories were supplied by non-obstructed bypass grafts or native coronary arteries (protected territory). However, 12 (29%) of these presented with a perfusion defect. In six cases, the perfusion defect involved myocardium distal to the graft-coronary anastomosis, as interpreted on the PET/CCTA fusion images. In turn, in 48 coronary territories the supplying artery was obstructed on CCTA (unprotected territory). Of these, 41 (85%, P < 0.001 vs. protected) presented with abnormal perfusion, involving myocardium distal to the anastomosis in 29 cases. Conclusion Hybrid imaging provides complementary information on the presence and localization of atherosclerotic lesions and myocardial perfusion abnormalities in symptomatic patients with previous CABG.

Sign in / Sign up

Export Citation Format

Share Document