Repeat Dose Toxicity Studies

Encyclopedia of Cancer ◽

10.1007/978-3-540-47648-1_5028 ◽

2008 ◽

pp. 2593-2594

Keyword(s):

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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L-citrulline: A preclinical safety biomarker for the small intestine in rats and dogs in repeat dose toxicity studies

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2021.107110 ◽

2021 ◽

pp. 107110

Author(s):

Sven Jäckel ◽

Frederic Christian Pipp ◽

Barbara Emde ◽

Stefan Weigt ◽

Enrico Vigna ◽

...

Keyword(s):

Small Intestine ◽

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies ◽

Preclinical Safety

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Rodent big brother: Development and validation of a home cage automated behavioural monitoring system for use in repeat-dose toxicity studies in rats

Toxicology Letters ◽

10.1016/j.toxlet.2014.06.206 ◽

2014 ◽

Vol 229 ◽

pp. S47-S48 ◽

Author(s):

Will S. Redfern ◽

J. Douglas Armstrong ◽

James Heward ◽

Ben Allison ◽

Tim Lukins ◽

...

Keyword(s):

Monitoring System ◽

Home Cage ◽

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies ◽

Big Brother ◽

Development And Validation

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Neurobehavioural assessments suitable for inclusion in repeat-dose toxicity studies on candidate drugs

Toxicology Letters ◽

10.1016/j.toxlet.2014.06.147 ◽

2014 ◽

Vol 229 ◽

pp. S31

Author(s):

Will Redfern

Keyword(s):

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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ORAL SINGLE-DOSE AND 13-WEEK REPEAT-DOSE TOXICITY STUDIES OF RCC-36, THE ACTIVE METABOLITE OF (±)-4-DIETHYLAMINO-1, 1-DIMETHYLBUT-2-YN-1-YL 2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETATE MONO-HYDROCHLORIDE MONOHYDRATE(NS-21), A NOVEL DRUG FOR URINARY FREQUENCY AND INCONTINENCE, IN RATS

The Journal of Toxicological Sciences ◽

10.2131/jts.22.supplementi_93 ◽

1997 ◽

Vol 22 (SupplementI) ◽

pp. 93-124

Author(s):

Shigenori FURUKAWA ◽

Hachiro KOUYAMA ◽

Mikito KIKUMORI ◽

Yuzou TANIGUCHI ◽

Tsukao NISHIMORI ◽

...

Keyword(s):

Single Dose ◽

Active Metabolite ◽

Repeat Dose ◽

Urinary Frequency ◽

Repeat Dose Toxicity ◽

Toxicity Studies ◽

Hydrochloride Monohydrate ◽

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REPEAT-DOSE TOXICITY STUDIES

Drug Safety Evaluation ◽

10.1002/9781119097440.ch8 ◽

2017 ◽

pp. 159-167 ◽

Keyword(s):

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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Repeat Dose Toxicity Studies

Preclinical Development Handbook ◽

10.1002/9780470249055.ch8 ◽

2008 ◽

pp. 213-232

Author(s):

Shayne Cox Gad

Keyword(s):

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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Inclusion of Safety Pharmacology Endpoints in Repeat-Dose Toxicity Studies

Principles of Safety Pharmacology - Handbook of Experimental Pharmacology ◽

10.1007/978-3-662-46943-9_14 ◽

2015 ◽

pp. 353-381 ◽

Author(s):

Will S. Redfern

Keyword(s):

Repeat Dose ◽

Safety Pharmacology ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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Repeat-Dose Toxicity Studies

Pharmaceutical Sciences Encyclopedia ◽

10.1002/9780470571224.pse134 ◽

2010 ◽

Keyword(s):

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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Safety assessment of astaxanthin from Haematococcus pluvialis: Acute toxicity, genotoxicity, distribution and repeat-dose toxicity studies in gestation mice

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2020.104695 ◽

2020 ◽

Vol 115 ◽

pp. 104695 ◽

Author(s):

Tingting Niu ◽

Jiawei Zhou ◽

Feng Wang ◽

Rongrong Xuan ◽

Juanjuan Chen ◽

...

Keyword(s):

Acute Toxicity ◽

Safety Assessment ◽

Haematococcus Pluvialis ◽

Repeat Dose ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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Statistical methodology to determine kinetically derived maximum tolerated dose in repeat dose toxicity studies

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2012.03.013 ◽

2012 ◽

Vol 63 (2) ◽

pp. 344-351 ◽

Author(s):

Lisa G. McFadden ◽

Michael J. Bartels ◽

David L. Rick ◽

Paul S. Price ◽

Donald D. Fontaine ◽

...

Keyword(s):

Maximum Tolerated Dose ◽

Repeat Dose ◽

Statistical Methodology ◽

Repeat Dose Toxicity ◽

Toxicity Studies

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