scholarly journals ORAL SINGLE-DOSE AND 13-WEEK REPEAT-DOSE TOXICITY STUDIES OF RCC-36, THE ACTIVE METABOLITE OF (±)-4-DIETHYLAMINO-1, 1-DIMETHYLBUT-2-YN-1-YL 2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETATE MONO-HYDROCHLORIDE MONOHYDRATE(NS-21), A NOVEL DRUG FOR URINARY FREQUENCY AND INCONTINENCE, IN RATS

1997 ◽  
Vol 22 (SupplementI) ◽  
pp. 93-124
Author(s):  
Shigenori FURUKAWA ◽  
Hachiro KOUYAMA ◽  
Mikito KIKUMORI ◽  
Yuzou TANIGUCHI ◽  
Tsukao NISHIMORI ◽  
...  
Keyword(s):  
Single Dose ◽  
Active Metabolite ◽  
Repeat Dose ◽  
Urinary Frequency ◽  
Repeat Dose Toxicity ◽  
Toxicity Studies ◽  
Hydrochloride Monohydrate ◽  
Novel Drug

Rodent big brother: Development and validation of a home cage automated behavioural monitoring system for use in repeat-dose toxicity studies in rats

2014 ◽  
Vol 229 ◽  
pp. S47-S48 ◽  
Author(s):  
Will S. Redfern ◽  
J. Douglas Armstrong ◽  
James Heward ◽  
Ben Allison ◽  
Tim Lukins ◽  
...  
Keyword(s):  
Monitoring System ◽  
Home Cage ◽  
Repeat Dose ◽  
Repeat Dose Toxicity ◽  
Toxicity Studies ◽  
Big Brother ◽  
Development And Validation

scholarly journals SINGLE-DOSE TOXICITY STUDIES OF PRULIFLOXACIN (NM441) IN MICE, RATS AND DOGS AND THE ACTIVE METABOLITE (NM394) IN RATS

1996 ◽  
Vol 21 (SupplementI) ◽  
pp. 33-44
Author(s):  
Hiroshi SHIMAZU ◽  
Yuji ISHIKAWA ◽  
Yasuyuki NISHIGUCHI ◽  
Masaru YOSHIDA ◽  
Keiko IWAKURA ◽  
...  
Keyword(s):  
Single Dose ◽  
Active Metabolite ◽  
Toxicity Studies
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