Nuclear Medicine in the Assessment of Painful Joint Prostheses

Author(s):  
Erik Vegt ◽  
Wim Schreurs ◽  
Martin Gotthardt ◽  
Wim J. G. Oyen
1982 ◽  
Vol &NA; (170) ◽  
pp. 156???168
Author(s):  
ROBERT SCHNEIDER ◽  
ROBERT H. FREIBERGER ◽  
BERNARD GHELMAN ◽  
CHITRANJAN S. RANAWAT

1984 ◽  
Vol 19 (5) ◽  
pp. 432-437 ◽  
Author(s):  
DONALD RESNICK ◽  
ROGER KERR ◽  
MICHAEL ANDRÈ ◽  
JOSE GUERRA ◽  
ROBERT O. CONE ◽  
...  

2017 ◽  
Vol 11 (1) ◽  
pp. 212-224 ◽  
Author(s):  
O.O. Adesanya ◽  
C.E. Hutchinson

Background:There is a long history of nuclear medicine developments in orthopaedics beginning in the early 20thcentury. Technetium-99m (99mTc) has a short half-life of six hours, emits 140 keV gamma rays and is the most widely used isotope, imaged with the Anger (gamma) camera. Gamma image quality and test sensitivity in painful prosthetic joints can be improved with single photon emission computed tomography (SPECT) and SPECT/CT. Positron Emission Tomography-Computed Tomography (PET-CT) with Sodium Fluoride (18F-NaF) and18Fluorine-fluorodeoxyglucose (18F-FDG) PET have promising and limited roles respectively in the investigation of painful prosthetic joints. New SPECT/CT and PET-CT isotopes targeting activated macrophages with99mTc Tilmanocept (Lymphoseek®) and68Gallium labelled Tilmanocept respectively show potential as agents to demonstrate wear particles ingested by macrophages and multinucleated giant cells. An imaging algorithm using SPECT and/or PET agents is proffered as a cost effective way of speedily and accurately arriving a diagnosis.Methods:Review of the historical role of nuclear medicine in orthopaedics and research into the potential role of new radiopharmaceutical agents was undertaken. Guidelines and algorithms for the imaging of complicated joint prosthesis are provided.Results:There is an established role for nuclear medicine in orthopaedics and particularly in the investigation of complicated joint prostheses. Imaging with Tilmanocept provides new opportunities to shorten the time to diagnose loosened and infected joint prostheses.Conclusion:There is a potential new role for Tilmanocept, which can be utilised with both PET-CT and SPECT-CT technologies. Tilmanocept is a relatively new radiopharmaceutical which has a potential role in the imaging assessment of painful joint prosthesis.


1984 ◽  
Vol 19 (5) ◽  
pp. S16
Author(s):  
Roger Kerr ◽  
Donald Resnick ◽  
Michael Andre ◽  
Jose Guerra ◽  
Robert O Cone ◽  
...  

2015 ◽  
Vol 36 (9) ◽  
pp. 931-940 ◽  
Author(s):  
Pelin Arican ◽  
Berna Okudan Tekin ◽  
Riza Şefizade ◽  
Seniha Naldöken ◽  
Aliye Baştuğ ◽  
...  

1990 ◽  
Vol 137 (3) ◽  
pp. 163 ◽  
Author(s):  
V.A. Oliveira ◽  
J.M. Nightingale

2020 ◽  
Vol 59 (04) ◽  
pp. 294-299 ◽  
Author(s):  
Lutz S. Freudenberg ◽  
Ulf Dittmer ◽  
Ken Herrmann

Abstract Introduction Preparations of health systems to accommodate large number of severely ill COVID-19 patients in March/April 2020 has a significant impact on nuclear medicine departments. Materials and Methods A web-based questionnaire was designed to differentiate the impact of the pandemic on inpatient and outpatient nuclear medicine operations and on public versus private health systems, respectively. Questions were addressing the following issues: impact on nuclear medicine diagnostics and therapy, use of recommendations, personal protective equipment, and organizational adaptations. The survey was available for 6 days and closed on April 20, 2020. Results 113 complete responses were recorded. Nearly all participants (97 %) report a decline of nuclear medicine diagnostic procedures. The mean reduction in the last three weeks for PET/CT, scintigraphies of bone, myocardium, lung thyroid, sentinel lymph-node are –14.4 %, –47.2 %, –47.5 %, –40.7 %, –58.4 %, and –25.2 % respectively. Furthermore, 76 % of the participants report a reduction in therapies especially for benign thyroid disease (-41.8 %) and radiosynoviorthesis (–53.8 %) while tumor therapies remained mainly stable. 48 % of the participants report a shortage of personal protective equipment. Conclusions Nuclear medicine services are notably reduced 3 weeks after the SARS-CoV-2 pandemic reached Germany, Austria and Switzerland on a large scale. We must be aware that the current crisis will also have a significant economic impact on the healthcare system. As the survey cannot adapt to daily dynamic changes in priorities, it serves as a first snapshot requiring follow-up studies and comparisons with other countries and regions.


1978 ◽  
Vol 17 (03) ◽  
pp. 110-125 ◽  
Author(s):  
O.P.D Noronha

A review is made of some of the factors affecting bioavailability of diagnostic 99mTc-radiopharmaceuticals currently used in the practice of nuclear medicine.


Sign in / Sign up

Export Citation Format

Share Document