Use of Time-Frequency Transforms and Kernel PCA to Classify Epileptic Patients from Control Subjects

Author(s):  
Samaneh Kazemifar ◽  
Reza Boostani
Author(s):  
M.I. Botez ◽  
Ezzedine Attig ◽  
Jean Lorrain Vézina

ABSTRACT:High-resolution CT scans of the brain and posterior fossa were performed on 106 phenytoin (PHT)- treated epileptics, 28 de novo epileptics and 43 control subjects. A higher incidence of cerebellar and brainstem (CBS) atrophy was observed in chronic PHT- or PHT+ phenobarbital-treated epileptics compared to the two other groups. Some control subjects and de novo epileptics presented mild CBS atrophy, whereas moderate to severe atrophy was noted exclusively in chronically-treated patients. In attempting to delineate the etiology of CBS atrophy, epileptic patients were divided in three groups: 55 subjects with normal CT scans, 30 with both cerebral and CBS atrophy, and 49 with pure CBS atrophy. Their ages, length of illness, number of generalized seizures, number of other seizures, and amount of PHT received during their lifetime were assessed. Statistical analysis revealed that posterior fossa atrophy in epileptics was significantly correlated with both the length of the illness and the amount of PHT ingested during the patient's lifetime. The number of seizures appears to not be related to CBS atrophy.


2018 ◽  
Author(s):  
Wang Zhigang ◽  
Zhang Lin ◽  
Xu jianhua ◽  
Wang Chongyang ◽  
Liu Zihao

1998 ◽  
Vol 23 (19) ◽  
pp. 1526 ◽  
Author(s):  
Miguel A. Muriel ◽  
José Azaña ◽  
Alejandro Carballar

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A173-A174
Author(s):  
R Stretch ◽  
M Zeidler

Abstract Introduction Manually scoring polysomnograms is both time-consuming and labor-intensive. It also increases variability in care. Generating features for use as components within larger models is an important part of building highly accurate auto-scoring systems. In this study, we examined the use of time-frequency data representations in combination with a convolutional neural networks (CNN). Methods We used just six (6) pre-scored polysomnograms from the MrOS dataset in this analysis. Only one electroencephalography (EEG) and one electrooculography (EOG) channel were extracted from each polysomnogram and split into 30 second epochs. Visual representations of each epoch in the time-frequency domain were generated using Morlet wavelets, then divided into training and validation sets in a 4:5 distribution. We then re-trained a ResNet-50 CNN using transfer learning to classify sleep stage based on the time-frequency representations. Results A total of 4971 epochs were generated. Of those, 1242 epochs formed the validation set. Performance was high for identifying Stage W with an accuracy of 94.2% (295/313 epochs). However, performance for other stages was considerably lower. Stage N3 was predicted correctly in 68.0% of cases (138/203 epochs), although in 60/75 cases of misclassification the predicted class was Stage N2. Similarly, Stage N2 was predicted correctly in 62.0% of cases (183/295 epochs), and in 63/112 cases of misclassification the predicted class was Stage N3. Accuracy for Stage REM was 64.9%. Stage N1 prediction was poor (22.0% accuracy), likely due to insufficient representation in the sample (< 10% of epochs). Conclusion This exploratory analysis of the use of time-frequency representations in conjunction with a CNN demonstrates some promise, especially with respect to prediction of Stage W using this technique. Inclusion of additional data channels and larger sample size would likely improve accuracy. Support RS - ASPIRE Fellowship (sponsored by the American Thoracic Association).


2001 ◽  
Vol 90 (1-2) ◽  
pp. 24-28 ◽  
Author(s):  
Christophe Baillard ◽  
Paulo Gonçalves ◽  
Laurence Mangin ◽  
Bernard Swynghedauw ◽  
Pascale Mansier

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