The Best Laid Plans of Mice and Men

Author(s):  
Roger P. Roess ◽  
Gene Sansone
Keyword(s):  
Author(s):  
Godfrey C. Hoskins ◽  
Betty B. Hoskins

Metaphase chromosomes from human and mouse cells in vitro are isolated by micrurgy, fixed, and placed on grids for electron microscopy. Interpretations of electron micrographs by current methods indicate the following structural features.Chromosomal spindle fibrils about 200Å thick form fascicles about 600Å thick, wrapped by dense spiraling fibrils (DSF) less than 100Å thick as they near the kinomere. Such a fascicle joins the future daughter kinomere of each metaphase chromatid with those of adjacent non-homologous chromatids to either side. Thus, four fascicles (SF, 1-4) attach to each metaphase kinomere (K). It is thought that fascicles extend from the kinomere poleward, fray out to let chromosomal fibrils act as traction fibrils against polar fibrils, then regroup to join the adjacent kinomere.


2018 ◽  
pp. 29-31
Author(s):  
David Miller

1989 ◽  
Vol 17 (2) ◽  
pp. 219-226
Author(s):  
Richard Allan Davison
Keyword(s):  

Author(s):  
Stephan Maxeiner ◽  
Selina Gebhardt ◽  
Frederick Schweizer ◽  
Agnes Venghaus ◽  
Gabriela Krasteva-Christ
Keyword(s):  

2019 ◽  
Vol 101 (1) ◽  
pp. 43-44
Author(s):  
Gerald L. Fowler

When Gerald Fowler began teaching 1st grade, he was sure the knowledge he’d gained from his master’s degree program had prepared him to create a classroom where students would be immersed in literacy learning from Day 1. From his studies, he’d come across the idea of introducing mice to the classroom to get students talking and building vocabulary skills. He opted instead for gerbils. One student’s surprising reaction to the gerbils taught Fowler about the complexities of language learning and the importance of experiences in increasing a child’s vocabulary.


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