Design of Novel Bioreductive Drugs

New Approaches in Cancer Pharmacology: Drug Design and Development ◽

10.1007/978-3-642-77874-2_7 ◽

1992 ◽

pp. 63-74

Author(s):

Paul Workman

Keyword(s):

Bioreductive Drugs

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Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069

British Journal of Cancer ◽

10.1038/bjc.1995.106 ◽

1995 ◽

Vol 71 (3) ◽

pp. 537-542 ◽

Author(s):

PL Olive

Keyword(s):

Bioreductive Drugs ◽

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Bioreductive Drugs and Radiation: Pharmacokinetics and Clinical Trials of Etanidazole Radiosensitizer

Selective Activation of Drugs by Redox Processes ◽

10.1007/978-1-4615-3768-7_27 ◽

1990 ◽

pp. 295-302

Author(s):

L. Busutti ◽

A. Petralia ◽

A. Breccia ◽

E. Ferri

Keyword(s):

Clinical Trials ◽

Bioreductive Drugs

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Targeting NMR Parameters and Dynamics of Radiosensitizers in Solution: Theoretical Studies of Prototypical Some Bioreductive Drugs

Structure-Activity Relationship Studies in Drug Development by NMR Spectroscopy ◽

10.2174/978160805164911101010145 ◽

2012 ◽

pp. 145-155

Author(s):

Bentham Science Publisher Bentham Science Publisher

Keyword(s):

Theoretical Studies ◽

Nmr Parameters ◽

Bioreductive Drugs

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BIOREDUCTIVE DRUGS - DUAL FUNCTION AGENTS AND RELATED COMPOUNDS

Congress Proceedings ◽

10.1016/b978-0-12-168562-1.50143-9 ◽

1992 ◽

pp. 802-806

Author(s):

G.E. Adams ◽

J. Bremner ◽

H.S. Edwards ◽

E.M. Fielden ◽

M. Naylor ◽

...

Keyword(s):

Dual Function ◽

Bioreductive Drugs ◽

Related Compounds

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MECHANISTIC STUDIES OF DIFFERENT CLASSES OF BIOREDUCTIVE DRUGS: IN VITRO AND IN VIVO

Radiation Research: A Twentieth-century Perspective ◽

10.1016/b978-0-12-168561-4.50349-8 ◽

1991 ◽

pp. 76

Author(s):

G.E. ADAMS ◽

I.J. STRATFORD ◽

E.M. FIELDEN ◽

M.A. NAYLOR

Keyword(s):

Mechanistic Studies ◽

Bioreductive Drugs

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Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs

British Journal of Cancer ◽

10.1038/bjc.1994.357 ◽

1994 ◽

Vol 70 (4) ◽

pp. 596-603 ◽

Author(s):

BG Siim ◽

GJ Atwell ◽

WR Wilson

Keyword(s):

Metabolic Activation ◽

Bioreductive Drugs

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Bioreductive Drugs: from Concept to Clinic

Clinical Oncology ◽

10.1016/j.clon.2007.03.006 ◽

2007 ◽

Vol 19 (6) ◽

pp. 427-442 ◽

Author(s):

S.R. McKeown ◽

R.L. Cowen ◽

K.J. Williams

Keyword(s):

Bioreductive Drugs

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Evaluation of bioreductive drugs in multicell spheroids

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/0360-3016(92)90504-b ◽

1992 ◽

Vol 22 (4) ◽

pp. 689-692 ◽

Author(s):

Ralph E. Durand ◽

Peggy L. Olive

Keyword(s):

Bioreductive Drugs

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Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

Carcinogenesis ◽

10.1093/carcin/20.3.415 ◽

1999 ◽

Vol 20 (3) ◽

pp. 415-419 ◽

Author(s):

Maria José Prieto-Alamo ◽

Francıoise Laval

Keyword(s):

Lethal Effect ◽

Bioreductive Drugs

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Exploiting hypoxia in solid tumors with DNA-targeted bioreductive drugs

Drugs of the Future ◽

10.1358/dof.2004.029.08.819391 ◽

2004 ◽

Vol 29 (8) ◽

pp. 807 ◽

Author(s):

M.V. Papadopoulou ◽

W.D. Bloomer

Keyword(s):

Solid Tumors ◽

Bioreductive Drugs

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