Synchronized Chaperone Function of Botulinum Neurotoxin Domains Mediates Light Chain Translocation into Neurons

2012 ◽  
pp. 115-137 ◽  
Author(s):  
Audrey Fischer
Keyword(s):  
Light Chain ◽  
Botulinum Neurotoxin ◽  
Chaperone Function

scholarly journals Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

mAbs ◽  
2014 ◽  
Vol 6 (2) ◽  
pp. 446-459 ◽  
Author(s):  
Sebastian Miethe ◽  
Christine Rasetti-Escargueil ◽  
Yvonne Liu ◽  
Siham Chahboun ◽  
Thibaut Pelat ◽  
...  
Keyword(s):  
Light Chain ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin A ◽  
Immune Library

scholarly journals 4-Amino-7-chloroquinolines: Probing Ligand Efficiency Provides Botulinum Neurotoxin Serotype A Light Chain Inhibitors with Significant Antiprotozoal Activity

2013 ◽  
Vol 56 (14) ◽  
pp. 5860-5871 ◽  
Author(s):  
Igor M. Opsenica ◽  
Mikloš Tot ◽  
Laura Gomba ◽  
Jonathan E. Nuss ◽  
Richard J. Sciotti ◽  
...  
Keyword(s):  
Light Chain ◽  
Botulinum Neurotoxin ◽  
Antiprotozoal Activity ◽  
Ligand Efficiency ◽  
Serotype A ◽  
Botulinum Neurotoxin Serotype A

scholarly journals Biofunctionalized Gold Nanoparticles for Colorimetric Sensing of Botulinum Neurotoxin A Light Chain

2014 ◽  
Vol 86 (5) ◽  
pp. 2345-2352 ◽  
Author(s):  
Xiaohu Liu ◽  
Yi Wang ◽  
Peng Chen ◽  
Yusong Wang ◽  
Jinling Zhang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Light Chain ◽  
Botulinum Neurotoxin ◽  
Colorimetric Sensing ◽  
Botulinum Neurotoxin A

scholarly journals High-Throughput Multiplex Flow Cytometry Screening for Botulinum Neurotoxin Type A Light Chain Protease Inhibitors

2010 ◽  
Vol 8 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Matthew J. Saunders ◽  
Steven W. Graves ◽  
Larry A. Sklar ◽  
Tudor I. Oprea ◽  
Bruce S. Edwards
Keyword(s):  
Flow Cytometry ◽  
Protease Inhibitors ◽  
High Throughput ◽  
Light Chain ◽  
Botulinum Neurotoxin ◽  
Type A ◽  
Botulinum Neurotoxin Type A
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