Decreased Detoxification Capacity of the Liver in Chronic Active Hepatitis (Observations in 224 patients)

Author(s):  
D. Müting ◽  
G. Winter ◽  
J. F. Kalk ◽  
R. Fischer
Author(s):  
Le Meizhao ◽  
Ye Ming ◽  
Song Xiaoming ◽  
Xu Jiazhang

“Hydropic degeneration” of the hepatocytes are often found in biopsy of the liver of some kinds of viral hepatitis. Light microscopic observation, compareted with the normal hepatocytes, they are enlarged, sometimes to a marked degree when the term “balloning” degeneration is used. Their cytoplasm rarefied, and show some clearness in the peripheral cytoplasm, so, it causes a hydropic appearance, the cytoplasm around the nuclei is granulated. Up to the present, many studies belive that main ultrastructural chenges of hydropic degeneration of the hepatocytes are results of the RER cristae dilatation with degranulation and disappearance of glycogen granules.The specimens of this study are fixed with the mixed fluid of the osmium acidpotassium of ferricyanide, Epon-812 embed. We have observed 21 cases of biopsy specimens with chronic severe hepatitis and severe chronic active hepatitis, and found that the clear fields in the cytoplasm actually are a accumulating place of massive glycogen. The granules around the nuclei are converging mitochondria, endoplasm reticulum and other organelles.


Kanzo ◽  
1986 ◽  
Vol 27 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Osami INOUE ◽  
Hideyo ITAKURA ◽  
Kan TORIYAMA ◽  
Masayoshi SHIMA ◽  
Akira SATO ◽  
...  

Gut ◽  
1991 ◽  
Vol 32 (5) ◽  
pp. 549-550 ◽  
Author(s):  
Y Ilan ◽  
M Hillman ◽  
R Oren ◽  
E Galun ◽  
M Shalit

1979 ◽  
Vol 67 (1) ◽  
pp. 117-121 ◽  
Author(s):  
David E. Hatoff ◽  
Manley Cohen ◽  
Byron F. Schweigert ◽  
Wilmier M. Talbert

2008 ◽  
Vol 19 ◽  
pp. S43
Author(s):  
BenJazia Ilhem ◽  
Khalifa Mabrouk ◽  
Ghannouchi Neirouz ◽  
Hachfi Wissem ◽  
Brahem Ahlem ◽  
...  

1987 ◽  
Vol 2 (3) ◽  
pp. 205-211 ◽  
Author(s):  
BARBARA A. LEGGETT ◽  
RUSSELL J. COLLINS ◽  
W. GRAHAM E. COOKSLEY ◽  
ROGER L. PRENTICE ◽  
LAWRIE W. POWELL

1980 ◽  
Vol 15 (1) ◽  
pp. 107-112 ◽  
Author(s):  
F. B. Crimmins ◽  
D. Adams ◽  
M. Ross ◽  
G. Ash ◽  
H. C. Thomas ◽  
...  

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