Cranial Mediastinal Thyroglossal Duct Adenocarcinoma in a Dog

ABSTRACT A 7 yr old female spayed Canaan dog was presented for evaluation of a subclinical intrathoracic mass noted during meta-static staging for a digit and lingual mass. Thoracic ultrasound and computed tomography revealed a 6.0 × 5.5 cm mass within the cranial mediastinum. The mass was septated with mixed fluid and soft-tissue structures and no evidence of vascular invasion. Narrow excision of the mass via a sternal thoracotomy was performed. Histopathology of the mass was consistent with a thyroglossal duct cyst adenocarcinoma. This is the first reported case of a thyroglossal duct cyst adenocarcinoma arising in the cranial mediastinum of a dog. There was no evidence of metastasis or recurrence 25 mo after surgery and adjunctive therapy.

Experimental Study on Water-Sand Seepage Characteristics in Fractured Rock Mass under Rheological Effect

This study investigates water-sand bursting disasters associated with fractured rock that affect safe mining in the mining areas of Western China. A broken rock water-sand seepage rheological test device was developed, and rheological tests were conducted on multiple groups of broken rock samples with single-stage axial loading and different load levels. When the rheology of each group of broken rock samples was stable, water-sand mixed fluid was injected into the samples at a certain pressure gradient to conduct water-sand seepage tests on broken rock masses. It was found that when the porosity of a fractured rock mass is within a certain range, the water-sand mixed fluid does not completely pass through the fractured rock mass and some sand particles are filtered by the fractured rock sample. There is an exponential relationship between the sand breaking ability and the sand filtration ability of fractured rock and its initial porosity, and the permeability of fractured rock decreases by a certain extent after sand filtration. However, for different load levels, when the flow through a fractured rock mass tends to be stable, the final porosity of the fractured rock mass decreases exponentially with axial compression. Based on the classical Kelvin rheological model and the basic theory of fractional calculus, a new fractional rheological model has been proposed and the rheological parameters under different load levels were fitted to the model. The new fractional rheological model is better able to describe the rheological characteristics of broken mudstone.

Modelling a Moving Propeller System in a Stratified Fluid Using OpenFOAM

Moving propeller systems can introduce significant disturbances in stratified environments by mixing the surrounding fluid. Restorative buoyancy forces subsequently act on this region/patch of mixed fluid, causing it to eventually collapse vertically and spread laterally in order to recover the original stratification. This work describes the use of an OpenFOAM solver, modified using existing functionality, to simulate a moving propeller system in a stratified environment. Its application considers a rotating KCD-32 propeller in a laboratory-scale wave tank which mimics published experiments on mixed patch collapse. The numerically-predicted collapse behaviour is compared with empirical data and scaling laws. The results agree closely, both qualitatively and quantitatively, thereby representing a successful step towards the validation of the numerical model.

Mixed fluid cosmological model in f(R, T) gravity

We construct a locally rotationally symmetric (LRS) Bianchi type-I cosmological model in f(R, T) theory of gravity when the source of gravitation is a mixture of barotropic fluid and dark energy (DE) by employing a time-varying deceleration parameter. We observe through the behavior of the state finder parameters (r, s) that our model begins from the Einstein static era and goes to ΛCDM era. The equation of state (EOS) parameter (ωd) for DE varies from the phantom (ω < –1) phase to quintessence (ω > –1) phase, which is consistent with observational results. It is found that the discussed model can reproduce the current accelerating phase of the expansion of the universe.

Experimental Investigation of Water–Sand Mixed Fluid Initiation and Migration in Porous Skeleton during Water and Sand Inrush

Water–sand inrush is one of the most serious disasters for mining in China. The evaluation of the occurrence and development of a high-concentration water and sand mixed fluid is an important issue for mining in China. In this study, contraposing to the 3 phases of water–sand inrush, three kinds of experiments are designed for the investigation of initiation, development, and occurrence of the disaster. A new sand–water transport testing system is setup to perform the tests. The results show that there are two key points in the disaster: (1) sand particle incipient motion and (2) porous skeleton structural instability. The incipient motion of sand grains is accompanied with the phenomena of volumetric dilatation and granular fluidization. The critical velocity of the incipient motion of the water–sand mixed fluid is significantly affected by the particle size and external stress. The interaction between water and sand grains is the key factor affecting the motion characteristics of water–sand mixture. When the hydraulic conditions exceed the threshold, the water and sand grains are mutually promoted, and the aquifer skeleton becomes unstable. Furthermore, during the water–sand inrush, the curves of volumetric flow rates of sand and water, respectively, for different samples manifest as two distinct waveforms.

Recommendation of an ideal mixed fluid preparation to be used as partial parenteral nutrition in surgical Neonatal Intensive Care Unit

Background: This study was conducted to assess the role of Partial Parenteral Nutrition (PPN) and a specially prepared “mixed fluid formula” used as PPN in sick surgical neonates.Methods: This single institution based Randomised Control Trial was performed in Surgical NICU of a tertiary care Centre. Surgical neonates who required bowel rest for >3 days like Esophageal Atresia (22), Duodenal Atresia (38), Jejuno-Ileal Atresia (50), Necrotising Enterocolitis (29) and others (11), were chosen. As a CONTROL population half (75) neonates were allowed maintenance fluid only (Isolyte P) and rest (75) were given a combination of maintenance fluid (Isolyte P) and PPN (specially prepared mixed fluid). This mixed fluid each 100 ml was prepared with 65ml Isolyte P, 15 ml 25% Dextrose, 10 ml Normal Saline, 7 ml Astymin 3, 2 ml Multivitamin and 1 ml Injection KCl. Fluid was continued till enteral feeding was established.Results: Neonates according to their body weight were divided in three groups <1 kg (50), 1-2.5 kg (71) and >2.5 kg (29) and their post-operative outcome was assessed as Clinical Positive/Negative and Laboratory Positive/Negative. Results were separately assessed in 3 body weight groups under “Control” and “Study” which showed both Clinical and Biochemical improvement in “Study group”.Conclusions: The composition of mixed fluid, its nutritional value, calorie supplementation, compatible osmolarity for peripheral venous administration and most importantly its easy and cost-effective preparation were assessed thoroughly and we recommend this “mixed fluid” preparation as a very useful PPN for sick surgical neonates.