Preparation of Isorhamnetin Molecularly Imprinted Polymer Microspheres by Modified Precipitation Polymerization

Author(s):  
Shuangshuang Dong ◽  
Yanbin Yun ◽  
Yunying Zhai
2011 ◽  
Vol 415-417 ◽  
pp. 1225-1230
Author(s):  
Chuan Yi Yao ◽  
Qing Qing Li ◽  
Ying Hua Lu

Molecular imprinting polymer microspheres were prepared by precipitation polymerization with methacrylic acid as functional monomer and 1-phenyl-1-propanol as template. The effects of synthesis conditions, including the kind of solvent, polymerization temperature, the concentration of template and initiator, rotational speed and pre-polymerization time, on the characteristics of the molecularly imprinted polymer microspheres were studied. The rebinding experiments showed that the molecularly imprinted polymer microspheres synthesized by precipitation polymerization at 60°C, with acetonitrile as solvent and the concentrations of both template and initiator of 0.01mol L-1, have good specific recognition and higher affinity capacity.


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