An immunohistochemical study of p53 and proliferating cell nuclear antigen expression in progressive multifocal leukoencephalopathy

1994 ◽  
Vol 88 (5) ◽  
pp. 465-471 ◽  
Author(s):  
G. Alistair Lammie ◽  
Andrew Beckett ◽  
Robert Courtney ◽  
Francesco Scaravilli
Keyword(s):  
Progressive Multifocal Leukoencephalopathy ◽  
Proliferating Cell Nuclear Antigen ◽  
Immunohistochemical Study ◽  
Antigen Expression ◽  
Nuclear Antigen ◽  
Proliferating Cell

Expression of p53 in human esophageal carcinoma: An immunohistochemical study with correlation to proliferating cell nuclear antigen expression

1992 ◽  
Vol 23 (11) ◽  
pp. 1238-1243 ◽  
Author(s):  
Hironobu Sasano ◽  
Shukichi Miyazaki ◽  
Yuji Gooukon ◽  
Tetsuro Nishihira ◽  
Takashi Sawai ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Proliferating Cell Nuclear Antigen ◽  
Immunohistochemical Study ◽  
Antigen Expression ◽  
Nuclear Antigen ◽  
Proliferating Cell

p53 and proliferating cell nuclear antigen expression in JC virus-infected cells of progressive multifocal leukoencephalopathy

1994 ◽  
Vol 25 (12) ◽  
pp. 1341-1345 ◽  
Author(s):  
Aurelio Ariza ◽  
JoséL. Mate ◽  
Angela Fernández-Vasalo ◽  
Carmen Gómez-Plaza ◽  
Javier Pérez-Piteira ◽  
...  
Keyword(s):  
Progressive Multifocal Leukoencephalopathy ◽  
Proliferating Cell Nuclear Antigen ◽  
Jc Virus ◽  
Antigen Expression ◽  
Nuclear Antigen ◽  
Infected Cells ◽  
Proliferating Cell

scholarly journals Immunohistochemical study of p53 and proliferating cell nuclear antigen expression in odontogenic keratocyst and periapical cyst

2014 ◽  
Vol 6 (5) ◽  
pp. 52 ◽  
Author(s):  
TharaPurath Sajeevan ◽  
TillaiRajasekaran Saraswathi ◽  
Kannan Ranganathan ◽  
Elizabeth Joshua ◽  
Uma DeviK Rao
Keyword(s):  
Proliferating Cell Nuclear Antigen ◽  
Immunohistochemical Study ◽  
Antigen Expression ◽  
Odontogenic Keratocyst ◽  
Nuclear Antigen ◽  
Periapical Cyst ◽  
Proliferating Cell

Growth kinetics of colorectal adenomacarcinoma sequence: An immunohistochemical study of proliferating cell nuclear antigen expression

1996 ◽  
Vol 27 (10) ◽  
pp. 1071-1076 ◽  
Author(s):  
Hsiao-bai Yang ◽  
Ping-i Hsu ◽  
Shih-huang Chan ◽  
Jenq-chang Lee ◽  
Jeng-shiann Shin ◽  
...  
Keyword(s):  
Growth Kinetics ◽  
Proliferating Cell Nuclear Antigen ◽  
Immunohistochemical Study ◽  
Antigen Expression ◽  
Nuclear Antigen ◽  
Proliferating Cell ◽  
Kinetics Of

The Impact of 5-Azacytidine on Placental Weight, Glycoprotein Pattern and Proliferating Cell Nuclear Antigen Expression in Rat Placenta

Placenta ◽  
2007 ◽  
Vol 28 (8-9) ◽  
pp. 803-811 ◽  
Author(s):  
L. Šerman ◽  
M. Vlahović ◽  
M. Šijan ◽  
F. Bulić-Jakuš ◽  
A. Šerman ◽  
...  
Keyword(s):  
Proliferating Cell Nuclear Antigen ◽  
Antigen Expression ◽  
Placental Weight ◽  
Nuclear Antigen ◽  
The Impact ◽  
Proliferating Cell

scholarly journals An evaluation of antioxidant effects on recovery from postischemic acute renal failure.

1994 ◽  
Vol 4 (8) ◽  
pp. 1588-1597
Author(s):  
R A Zager ◽  
S M Fuerstenberg ◽  
P H Baehr ◽  
D Myerson ◽  
B Torok-Storb
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Dna Fragmentation ◽  
Proliferating Cell Nuclear Antigen ◽  
Antigen Expression ◽  
Nuclear Antigen ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Tubular Necrosis ◽  
Proliferating Cell

Xanthine oxidase (XO) activity and hydroxyl radical (.OH) formation are widely proposed mediators of renal reperfusion injury, potentially altering the severity of, and recovery from, postischemic acute renal failure. The goal of this study was to ascertain whether combination XO inhibitor (oxypurinol) and .OH scavenger (Na benzoate) therapy, given at the time of renal ischemia, alters the extent of: (1) tubular necrosis and filtration failure; (2) DNA fragmentation/apoptosis (assessed in situ by terminal deoxynucleotidyl transferase reactivity); (3) early tubular regenerative responses (proliferating cell nuclear antigen expression; (3H)thymidine incorporation); and (4) the rate and/or degree of functional and morphologic repair. The effects of XO inhibition, .OH scavengers, and "catalytic" iron (FeSO4) on human proximal tubular cell proliferation in vitro were also assessed with a newly established cell line (HK-2). Male Sprague-Dawley rats were subjected to 35 min of bilateral renal arterial occlusion with or without oxypurinol/benzoate therapy. These agents did not alter the extent of tubular necrosis or filtration failure, proliferating cell nuclear antigen expression or thymidine incorporation, or the rate/extent of renal functional/morphologic repair. DNA fragmentation did not precede tubular necrosis, and it was unaffected by antioxidant therapy. By 5 days postischemia, both treatment groups demonstrated regenerating epithelial fronds that protruded into the lumina. These structures contained terminal deoxynucleotidyl transferase-reactive, but morphologically intact, cells, suggesting the presence of apoptosis. Oxypurinol and .OH scavengers (benzoate; dimethylthiourea) suppressed in vitro tubular cell proliferation; conversely, catalytic Fe had a growth-stimulatory effect. These results suggest that: (1) XO inhibition/.OH scavenger therapy has no discernible net effect on postischemic acute renal failure; (2) DNA fragmentation does not precede tubular necrosis, suggesting that it is not a primary mediator of ischemic cell death; and (3) antioxidants can be antiproliferative for human tubular cells, possibly mitigating their potential beneficial effects.

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