Casings for electronic medical instruments and apparatuses

1968 ◽  
Vol 2 (3) ◽  
pp. 169-172
Author(s):  
E. L. Vainer
Keyword(s):  
Medical Instruments

Innovative medical instruments data platform and service ecosystem construction

2021 ◽  
Author(s):  
Lei Wang ◽  
Kun Han ◽  
Qing Qian ◽  
Qiang Zhang ◽  
Jishuai Wang ◽  
...  
Keyword(s):  
Data Platform ◽  
Medical Instruments ◽  
Service Ecosystem

Classification and description of clamping type medical instruments

1968 ◽  
Vol 2 (6) ◽  
pp. 335-338
Author(s):  
M. I. Vorotyntseva ◽  
Yu. F. Kabatov
Keyword(s):  
Medical Instruments

Residual tensions in drawn tubes used as tubular parts of medical instruments. First communication

1968 ◽  
Vol 2 (1) ◽  
pp. 29-33
Author(s):  
E. L. Vainer
Keyword(s):  
Medical Instruments

Software validation of medical instruments

2014 ◽  
Author(s):  
Davidson R. Boccardo ◽  
Raphael C. S. Machado ◽  
Sergio M. Camara ◽  
Charles B. do Prado ◽  
Wilson S. Melo ◽  
...  
Keyword(s):  
Software Validation ◽  
Medical Instruments

Acute pulmonary toxic effects of chlorhexidine (CHX) following an intratracheal instillation in rats

2011 ◽  
Vol 30 (11) ◽  
pp. 1795-1803 ◽  
Author(s):  
Yuying Xue ◽  
Shanshan Zhang ◽  
Yang Yang ◽  
Minyu Lu ◽  
Yiqing Wang ◽  
...  
Keyword(s):  
Distress Syndrome ◽  
Intratracheal Instillation ◽  
Target Organ ◽  
Toxic Effects ◽  
Cytotoxic Action ◽  
Blood Cell Count ◽  
Inflammatory Reactions ◽  
Medical Instruments ◽  
Mucous Membranes ◽  
Alveolar Edema

Chlorhexidine (CHX) is a cationic biguanide compound that has been widely used for disinfection of skin, mucous membranes, and medical instruments. Poisoning has been occurred occasionally due to its easy accessibility. Some fatal cases developed acute respiratory distress syndrome (ARDS) from aspiration of CHX directly into the lung. There is no preclinical information about the pulmonary toxicity of CHX available since the products of CHX are usually developed for disinfection by topical use. In this study, the acute pulmonary toxic effects of CHX following an intratracheal instillation in rats were investigated. Rats were exposed either to CHX at concentrations of 0.02% and 0.2% or to distilled water at a volume of 500 μl/kg b.w. CHX at concentration of 0.2% caused changes in hematological and biochemical values including white blood cell count (WBC), total protein (TP), albumin (ALB), lactate dehydrogenase (LDH), blood urea nitrogen (BUN) and creatinine (CRE), and induced inflammatory reactions including intra-alveolar edema and hemorrhages, as well as resulted in the target organ concentration in lungs at the level of about 1.0 μg/g and maintained for more than 1 week, when administered intratracheally in rats. The cytotoxic action of CHX might induce those detrimental reactions in rats.

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