Periaqueductal tumor as a cause of late-onset aqueductal stenosis

1987 ◽  
Vol 3 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Paul Steinbok ◽  
Michael Charles Boyd
Keyword(s):  
Late Onset ◽  
Aqueductal Stenosis ◽  
Periaqueductal Tumor

Periaqueductal Tumor as a Cause of Late-onset Aqueductal Stenosis

1990 ◽  
pp. 138-138
Author(s):  
Paul Steinbok ◽  
Michael Charles Boyd
Keyword(s):  
Late Onset ◽  
Aqueductal Stenosis ◽  
Periaqueductal Tumor

scholarly journals Hydrocephalus presenting as idiopathic aqueductal stenosis with subsequent development of obstructive tumor: report of 2 cases demonstrating the importance of serial imaging

2017 ◽  
Vol 20 (4) ◽  
pp. 329-333 ◽  
Author(s):  
Jarod L. Roland ◽  
Richard L. Price ◽  
Ashwin A. Kamath ◽  
S. Hassan Akbari ◽  
Eric C. Leuthardt ◽  
...  
Keyword(s):  
Late Onset ◽  
Diagnostic Testing ◽  
Subsequent Development ◽  
Mass Effect ◽  
Aqueductal Stenosis ◽  
Pineal Region ◽  
Serial Imaging ◽  
Cerebrospinal Fluid Diversion ◽  
First Case

The authors describe 2 cases of triventricular hydrocephalus initially presenting as aqueductal stenosis that subsequently developed tumors of the pineal and tectal region. The first case resembled late-onset idiopathic aqueductal stenosis on serial imaging. Subsequent imaging revealed a new tumor in the pineal region causing mass effect on the midbrain. The second case presented in a more typical pattern of aqueductal stenosis during infancy. On delayed follow-up imaging, an enlarging tectal mass was discovered. In both cases hydrocephalus was successfully treated by cerebrospinal fluid diversion prior to tumor presentation. The differential diagnoses, diagnostic testing, and treatment course for these unusual cases are discussed. The importance of follow-up MRI in cases of idiopathic aqueductal stenosis is emphasized by these exemplar cases.

scholarly journals Third Ventriculostomy in Late-onset Idiopathic Aqueductal Stenosis Treatment: A Focus on Clinical Presentation and Radiological Diagnosis

2014 ◽  
Vol 54 (12) ◽  
pp. 1014-1021 ◽  
Author(s):  
Marco LOCATELLI ◽  
Riccardo DRAGHI ◽  
Andrea DI CRISTOFORI ◽  
Giorgio CARRABBA ◽  
Mario ZAVANONE ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Late Onset ◽  
Aqueductal Stenosis ◽  
Radiological Diagnosis ◽  
Third Ventriculostomy

MR Imaging in Intrinsic Tectal Tumours

1997 ◽  
Vol 10 (4) ◽  
pp. 459-464
Author(s):  
G. Sparacia ◽  
S. Pappalardo ◽  
L. Manfrè ◽  
C. Sarno ◽  
T. Angileri ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Late Onset ◽  
Aqueductal Stenosis ◽  
Low Grade ◽  
Multiplanar Imaging ◽  
Show Evidence ◽  
Long Term Follow Up ◽  
Progressive Growth ◽  
Work Up

This article presents some anatomic and neuroradiologic clues in the identification of intrinsic tectal tumours and the main related problems of differential diagnosis. The majority of intrinsic tectal lesions are low-grade gliomas that have been recognized as a potential cause of late-onset aqueductal stenosis. The superb sensitivity of magnetic resonance (MR) imaging and its multiplanar imaging capability allow an optimal diagnostic accuracy in the tectal region. For this reason, MR imaging should be included in the work-up of all patients with neurological findings of brain stem dysfunction and late-onset aqueductal stenosis. Tectal gliomas particularly merit an accurate MR long-term follow-up monitoring, since they may ultimately show evidence of progressive growth and require therapeutic intervention to maintain disease control.

The long-term outcome in children with late-onset aqueductal stenosis resulting from benign intrinsic tectal tumors

1994 ◽  
Vol 80 (4) ◽  
pp. 681-688 ◽  
Author(s):  
Ian F. Pollack ◽  
Dachling Pang ◽  
A. Leland Albright
Keyword(s):  
Mr Imaging ◽  
Late Onset ◽  
Aqueductal Stenosis ◽  
Mr Studies ◽  
Low Grade ◽  
Shunt Insertion ◽  
Content Type ◽  
Fine Print

✓ Benign intrinsic tumors arising in the dorsal midbrain have long been recognized as a potential cause of late-onset aqueductal stenosis. Where histopathological studies of such lesions have been performed, the majority have been reported to be low-grade gliomas. Because these tumors often present with a paucity of neurological findings and a characteristic radiographic appearance and because there has been substantial uncertainty regarding their potential for long-term progression, the authors have routinely deferred biopsy and/or radiotherapy for these lesions until there has been clear-cut evidence of disease progression. Herein, the authors report their experience with 16 children manifesting this syndrome who were treated between 1979 and 1992. The patients ranged in age from 6 months to 14 years at presentation (median 9.75 years). In general, symptoms of increased intracranial pressure developed insidiously; three of the older children had exhibited profound macrocephaly since infancy, which predated the onset of other symptoms of hydrocephalus by several years. Only one of the 16 children showed evidence of brain-stem dysfunction at presentation, a partial Parinaud's syndrome that resolved following placement of a ventriculoperitoneal shunt. In 12 patients, the tumor was detected by magnetic resonance (MR) imaging at initial evaluation as a bulbous enlargement of the tectal plate. In four patients who presented before the advent of MR imaging, initial computerized tomography (CT) scans failed to delineate the tectal lesion convincingly; however, subsequent MR studies clearly demonstrated the presence of an intrinsic tectal mass. All 16 patients underwent cerebrospinal fluid diversion initially, with conservative management of the tectal lesion and close long-term follow-up monitoring. Four children ultimately demonstrated clinical signs of progressive tumor growth with the insidious onset of partial or complete Parinaud's syndrome, despite the presence of a functioning shunt. The median interval to symptom progression was 7.8 years from the time of shunt insertion and 11.5 years from the onset of initial symptoms and signs of hydrocephalus. Follow-up CT and MR studies demonstrated obvious tumor enlargement in three of the four patients who then underwent stereotactic or open biopsy. The histological diagnosis in these three was benign mixed glioma, anaplastic astrocytoma, and low-grade astrocytoma. All four patients with clinical evidence of disease progression were treated with conventional radiotherapy; the patient with an anaplastic astrocytoma also received focal stereotactic radiosurgery. These patients subsequently remained clinically stable, with three showing tumor regression and one showing stable disease on serial MR studies (median follow-up period from tumor progression, 4.25 years). One other child was noted to have progressive tumor enlargement during the 2 years after shunt insertion; she remains asymptomatic and has not yet undergone biopsy or radiotherapy. It is concluded that benign intrinsic tectal tumors, although generally indolent, merit conscientious long-term follow-up monitoring since these lesions may ultimately show evidence of progressive growth and require therapeutic intervention to maintain disease control. These tumors are best visualized on MR imaging, which should be included in the workup of all patients with late-onset aqueductal stenosis.

scholarly journals Intracranial pressure waveform characteristics in idiopathic normal pressure hydrocephalus and late-onset idiopathic aqueductal stenosis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Lauren M. Green ◽  
Thomas Wallis ◽  
Martin U. Schuhmann ◽  
Matthias Jaeger
Keyword(s):  
Intracranial Pressure ◽  
Normal Pressure Hydrocephalus ◽  
Late Onset ◽  
Normal Pressure ◽  
Aqueductal Stenosis ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Reserve Capacity ◽  
Icp Monitoring ◽  
Pulse Wave Amplitude ◽  
Compensatory Reserve

Abstract Background Idiopathic normal pressure hydrocephalus (iNPH) and late-onset idiopathic aqueductal stenosis (LIAS) are two forms of chronic adult hydrocephalus of different aetiology. We analysed overnight intracranial pressure (ICP) monitoring to elucidate ICP waveform changes characteristic for iNPH and LIAS to better understand pathophysiological processes of both diseases. Methods 98 patients with iNPH and 14 patients with LIAS from two neurosurgical centres were included. All patients underwent diagnostic overnight computerised ICP monitoring with calculation of mean ICP, ICP heartbeat related pulse wave amplitude calculated in the frequency domain (AMP) and the time domain (MWA), index of cerebrospinal compensatory reserve (RAP) and power of slow vasogenic waves (SLOW). Results ICP was higher in LIAS than iNPH patients (9.3 ± 3.0 mmHg versus 5.4 ± 4.2 mmHg, p = 0.001). AMP and MWA were higher in iNPH versus LIAS (2.36 ± 0.91 mmHg versus 1.81 ± 0.59 mmHg for AMP, p = 0.012; 6.0 ± 2.0 mmHg versus 4.9 ± 1.2 mmHg for MWA, p = 0.049). RAP and SLOW indicated impaired reserve capacity and compliance in both diseases, but did not differ between groups. INPH patients were older than LIAS patients (77 ± 6 years versus 54 ± 14 years, p < 0.001). Conclusions ICP is higher in LIAS than in iNPH patients, likely due to the chronically obstructed CSF flow through the aqueduct, but still in a range considered normal. Interestingly, AMP/MWA was higher in iNPH patients, suggesting a possible role of high ICP pulse pressure amplitudes in iNPH pathophysiology. Cerebrospinal reserve capacity and intracranial compliance is impaired in both groups and the pressure-volume relationship might be shifted towards lower ICP values in iNPH. The physiological influence of age on ICP and AMP/MWA requires further research.

scholarly journals Evaluation of Late Onset Congenital Aqueductal Stenosis Hydrocephalus

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Hassan Mohammed
Keyword(s):  
Late Onset ◽  
Aqueductal Stenosis

Late-onset adult hydrocephalus secondary to aqueductal stenosis

2013 ◽  
pp. 232-233
Author(s):  
Nafi Aygun ◽  
Gaurang Shah ◽  
Dheeraj Gandhi
Keyword(s):  
Late Onset ◽  
Aqueductal Stenosis
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