Immunologic response of mouse spleen cells during induction of tolerance in the early postnatal period

1970 ◽  
Vol 69 (5) ◽  
pp. 548-549
Author(s):  
I. N. Maiskii ◽  
G. P. Airapet'yan ◽  
T. A. Pokrovskaya
1969 ◽  
Vol 68 (3) ◽  
pp. 1014-1015
Author(s):  
I. N. Maiskii ◽  
T. A. Pokrovskaya ◽  
G. P. Airapet'yan

1974 ◽  
Vol 5 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Iris A. Ly ◽  
Robert I. Mishell
Keyword(s):  

1976 ◽  
Vol 144 (4) ◽  
pp. 996-1008 ◽  
Author(s):  
J R Neefe ◽  
D H Sachs

Monolayers formed of normal mouse spleen cells attached to polystyrene coated with poly-L-lysine were tested for their ability to bind specifically antigen-reactive cells in normal or primed mouse spleen. 88 to greater than 98% of the activity of cytotoxic populations was removed by a single adsorption. However, normal spleen cells or spleen cells previously primed in vitro could not be depleted of their capacity to be sensitized, even when adsorption effectively removed all residual cytotoxic activity from the same previously primed population. In fact, exposure to an immunoadsorbent augmented the ultimate cytotoxicity generated in a nonspecific fashion. This augmentation was especially dramatic in the case of a previously primed population and may have reflected the removal of a nonspecific suppressor. If antigen-reactive precursors cannot be removed efficiently by adsorption, other approaches to the generation of tolerant lymphoid populations, such as specific suppression of precursor differentiation must be sought.


Reproduction ◽  
1993 ◽  
Vol 97 (1) ◽  
pp. 13-20 ◽  
Author(s):  
L. Pinilla ◽  
E. Trimino ◽  
P. Garnelo ◽  
C. Bellido ◽  
R. Aguilar ◽  
...  

Midwifery ◽  
2009 ◽  
Vol 25 (6) ◽  
pp. 665-672 ◽  
Author(s):  
Ü. Sevil ◽  
S. Özkan

Author(s):  
Elena Vasilevna Kuzminova ◽  
Vladimir Anatolevich Grin ◽  
Marina Petrovna Semenenko ◽  
Andrey Georgievich Koshchaev ◽  
Oleg Yurievich Chernykh

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