Azidomorphine is an agonist of high-affinity opioid receptor binding sites

1986 ◽  
Vol 11 (11) ◽  
pp. 1565-1569
Author(s):  
Katalin Horv�th ◽  
M�ria Wollemann
1985 ◽  
Vol 146 (5) ◽  
pp. 507-509 ◽  
Author(s):  
F. Owen ◽  
R. C. Bourne ◽  
M. Poulter ◽  
T. J. Crow ◽  
S. J. Paterson ◽  
...  

SummaryOpioid receptor binding sites were assessed in membrane preparations of caudate nucleus from post-mortem brains of controls and of patients with schizophrenia. There was no difference between the two groups in the total specific binding of 3H-etorphine or in its ‘μ’ and (‘δ+χ’) components. Similarly, the binding of 3H-naloxone did not differ between patients and controls. It is concluded that a previous report of reduced opioid receptors in caudate of schizophrenics is unlikely to prove a consistent finding and that the results of the present study offer no support to the claim that there is a general disturbance in opiate mechanisms in schizophrenia.


1996 ◽  
Vol 4 (12) ◽  
pp. 2151-2166 ◽  
Author(s):  
Takeshi Sagara ◽  
Hiromu Egashira ◽  
Mikako Okamura ◽  
Ikuo Fujii ◽  
Yasuyuki Shimohigashi ◽  
...  

1990 ◽  
Vol 100 (2) ◽  
pp. 319-323 ◽  
Author(s):  
J.R. Traynor ◽  
J.C Hunter ◽  
R.E. Rodriguez ◽  
R.G. Hill ◽  
J. Hughes

1987 ◽  
Vol 19 (5) ◽  
pp. 611-615 ◽  
Author(s):  
C. Pilapil ◽  
S. Welner ◽  
J. Magnan ◽  
S. Gauthier ◽  
R. Quirion

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