Effect of substances blocking calcium channels (verapamil, D-600, manganese ions) on transmitter release from motor nerve endings in frog muscle

1978 ◽  
Vol 9 (4) ◽  
pp. 320-325 ◽  
Author(s):  
I. M. Gotgil'f ◽  
L. G. Magazanik

1978 ◽  
Vol 200 (1139) ◽  
pp. 225-230 ◽  

β-Bungarotoxin (β-BuTX) induces twitching of innervated frog muscle and subsequently blocks transmitter release from motor nerve endings. These actions of β-BuTX are prevented if the nerve-muscle junctions are pretreated with a low concentration of phospholipase A 2 from bee venom. When the Ca 2+ in the external fluid is replaced by Sr 2+ , the phospho­lipase activity of β-BuTX is negligible and, in these conditions, β-BuTX causes a decrease in the amplitude of endplate potentials but does not go on to block transmitter release completely.



1974 ◽  
Vol 187 (1087) ◽  
pp. 235-241 ◽  

Non-heated rabbit serum causes massive transmitter release from motor nerve endings. The effect is not observed after heating the serum, in the way usually done to destroy complement. It seems that serum may be acting on the nerve terminals by a mechanism involving the complement system in the absence of antibody.



2006 ◽  
Vol 99 (2-3) ◽  
pp. 1
Author(s):  
Rachid Giniatullin ◽  
Serguey Grishin ◽  
Arthur Giniatullin








1989 ◽  
Vol 77 (2-3) ◽  
pp. 79-91 ◽  
Author(s):  
J. Molg� ◽  
M. P�cot-Dechavassine ◽  
S. Thesleff




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