Successful treatment of aTrichosporon beigelii septicemia in a granulocytopenic patient with amphotericin B and granulocyte colony-stimulating factor

Infection ◽  
1994 ◽  
Vol 22 (4) ◽  
pp. 283-286 ◽  
Author(s):  
M. E. Grauer ◽  
C. Bokemeyer ◽  
W. Bautsch ◽  
M. Freund ◽  
H. Link
1995 ◽  
Vol 50 (3) ◽  
pp. 227-227 ◽  
Author(s):  
Hiroshi Sato ◽  
Hakumei Oh ◽  
Rhuko Cho ◽  
Hirotoshi Nakamura ◽  
Takayoshi Asai

Thyroid ◽  
1998 ◽  
Vol 8 (9) ◽  
pp. 791-794 ◽  
Author(s):  
P. MEZQUITA ◽  
V. LUNA ◽  
M. MUÑOZ-TORRES ◽  
E. TORRES-VELA ◽  
F. LOPEZ-RODRIGUEZ ◽  
...  

1992 ◽  
Vol 80 (4) ◽  
pp. 557-559 ◽  
Author(s):  
Rudolf Weide ◽  
Hubert Köppler ◽  
Jochen Heymanns ◽  
Karl-Heinz Pflüuger ◽  
Klaus Havemann

2007 ◽  
Vol &NA; ◽  
pp. S25-S26 ◽  
Author(s):  
Wipada Pariyaprasert ◽  
Nualanong Visitsunthorn ◽  
Pakit Vichyanond ◽  
Orathai Jirapongsananuruk

1998 ◽  
Vol 42 (9) ◽  
pp. 2299-2303 ◽  
Author(s):  
Shefali Vora ◽  
Sharda Chauhan ◽  
Elmer Brummer ◽  
David A. Stevens

ABSTRACT Voriconazole (VCZ) was tested for antifungal activity againstAspergillus fumigatus hyphae alone or in combination with neutrophils or monocytes. Antifungal activity was measured as percent inhibition of hyphal growth in assays using the dye MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] or XTT [2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide]. With both assays, VCZ inhibited hyphal growth at concentrations of <1 μg/ml and was almost as active as amphotericin B. VCZ (0.6 μg/ml) was sporicidal, as was amphotericin B (0.4 μg/ml). With both the MTT and XTT assays, neutrophils alone inhibited hyphae; when combined with VCZ, there was additive activity. Both granulocyte colony-stimulating factor- and granulocyte-macrophage colony-stimulating factor (GM-CSF)-treated polymorphonuclear neutrophils (PMN) had enhanced inhibition of hyphal growth. Moreover, such treatment of PMN also enhanced the collaboration of PMN with VCZ. Monocytes inhibited hyphal growth. When VCZ was combined with monocytes or monocytes were treated with GM-CSF, inhibition was significantly increased, to similar levels. However, the combination of VCZ with GM-CSF treatment of monocytes did not significantly increase the high-level inhibition by monocytes with either agent alone.


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