Effects of trifluoperazine and chlorpromazine on calciumrepleted injury in isolated ventricle strips

1985 ◽  
Vol 80 (5) ◽  
pp. 556-563 ◽  
Author(s):  
K. Okumura ◽  
K. Ogawa ◽  
T. Satake
Keyword(s):  
Isolated Ventricle

scholarly journals Experimentally induced automatism in rat isolated ventricle

1972 ◽  
Vol 46 (1) ◽  
pp. 167-169 ◽  
Author(s):  
P. D. Garcia Jalón ◽  
J. P. Moratinos ◽  
J. S. Serrano
Keyword(s):  
Isolated Ventricle ◽  
Experimentally Induced

Megachoroid as a cause of isolated ventricle syndrome

1989 ◽  
Vol 5 (3) ◽  
pp. 194-196 ◽  
Author(s):  
William M. Chadduck ◽  
Charles M. Glasier
Keyword(s):  
Isolated Ventricle

EXPERIENCES WITH THE 'VENUS' HEART METHOD FOR DETERMINING ACETYLCHOLINE

1948 ◽  
Vol 26e (2) ◽  
pp. 183-187 ◽  
Author(s):  
Donald B. Tower ◽  
Donald McEachern
Keyword(s):  
Test Object ◽  
Biological Materials ◽  
Isolated Ventricle

Experiences with a little known method for determining acetylcholine in biological materials are reported. The test object is the isolated ventricle of the quahaug, Venus mercenaria, a preparation that is stable for many hours. Its minimal sensitivity for acetylcholine is between 0.005 and 0.01 µgm. %. The method is simple and highly specific, and the preparation may be used repeatedly, as often as every 5 to 10 min. Details of the method with illustrative results are given.

scholarly journals The influence of mechanical conditions of the circulation on the electrocardiogram

1923 ◽  
Vol 95 (667) ◽  
pp. 279-298 ◽  
Keyword(s):  
Heart Rate ◽  
Heart Muscle ◽  
Electrical Response ◽  
Venous Pressure ◽  
Initial Tension ◽  
Intraventricular Conduction ◽  
Mammalian Heart ◽  
Isolated Ventricle ◽  
T Waves

Previous Work .—As a preliminary to the investigation of the effect of work on the mammalian heart it was advisable to carry out experiments on the cold-blooded heart in order to determine the relations of the electrical deflections to the amount of work performed. Special attention was paid to the duration of the electrical response and the constancy of the heart rate. The isolated ventricle of the tortoise ( Testudo grœca ) was used. In the frog’s heart Straub (1) measured the effect on the electrogram (direct leads) of increasing the filling and initial tension. Under these conditions he noted that the R' and T' waves were diminished in size. Seeman (2), working on the same animal but using a slightly different method, found that with increased venous pressure R' and T' diminished in the same ratio; little or no change in the electrogram was noticed on raising the pressure against which the heart contracted. If The heart was allowed to beat under isometric conditions, R' and T' diminished as the venous pressure was raised, until a certain level was reached; at this point the amplitude of the deflections showed no further alterations. Seeman concluded that these changes were not brought about by the augmented work of the heart muscle but by the adjustment of tension differences during contraction. Working on the frog’s heart, Dale and Mines (3) demonstrated the balance between the frequency of beat, the duration of electrical response, auriculo-ventricular and intraventricular conduction; they also showed the effects of nervous influences on these factors.

scholarly journals The anaerobic breakdown of carbohydrate in the isolated ventricle of the frog

1934 ◽  
Vol 80 (4) ◽  
pp. 457-479 ◽  
Author(s):  
R. Gaddie ◽  
C. P. Stewart
Keyword(s):  
Isolated Ventricle

scholarly journals Ischemic preconditioning: antiarrhythmic effects and electrophysiological mechanisms in isolated ventricle

1998 ◽  
Vol 274 (1) ◽  
pp. H66-H75 ◽  
Author(s):  
Jiequan Zhu ◽  
Gregory R. Ferrier
Keyword(s):  
Ischemic Preconditioning ◽  
Conduction Block ◽  
Conduction Time ◽  
Ischemia And Reperfusion ◽  
Early Reperfusion ◽  
Ventricular Tissue ◽  
Block Preconditioning ◽  
Isolated Ventricle ◽  
Premature Beats ◽  
Antiarrhythmic Effects

The objective of this study was to identify cellular electrophysiological mechanisms by which ischemic preconditioning decreases arrhythmias in an isolated ventricular tissue model of ischemia and reperfusion. Electrical activity was recorded with microelectrodes from endocardium and epicardium of paced guinea pig right ventricular free walls. Control preparations were exposed for 15 min to Tyrode solution modified to simulate selected ischemic conditions and then were reperfused for 30 min with normal solution. Preconditioned tissues were exposed to a 2- or 5-min period of simulated ischemia before this same protocol. Neither preconditioning protocol affected incidence of ventricular tachycardia (VT) in ischemia; however, the 5-min protocol significantly decreased premature beats (PVB) and transmural conduction block. Preconditioning for 5 min, but not 2 min, significantly decreased reperfusion-induced VT and PVB. Ischemic preconditioning did not change effects of ischemia or reperfusion on action potential duration, effective refractory period, or endocardial conduction time. However, preconditioning markedly attenuated depression of transmural conduction by ischemia and early reperfusion and thereby prevented conduction delays necessary for transmural reentry.

The relation of neurohumors to autorhythmicity of the isolated ventricle of Strombus gigas (Gastropoda prosobranchia)

1968 ◽  
Vol 24 (1) ◽  
pp. 19-30 ◽  
Author(s):  
Robert B. Hill ◽  
William N. Thibault
Keyword(s):  
Strombus Gigas ◽  
Isolated Ventricle

Mixing action and mitral inflow patterns in an isolated ventricle hydraulically operated

1974 ◽  
Vol 8 (4) ◽  
pp. 517-525
Author(s):  
R. A. LLOYD ◽  
D. A. MCDONALD
Keyword(s):  
Mitral Inflow ◽  
Isolated Ventricle

Effects of Trifluoperazine and Chlorpromazine on Calcium Paradox in Isolated Ventricle Strips

1985 ◽  
pp. 239-249
Author(s):  
Kenji Okumura ◽  
Kouichi Ogawa ◽  
Tatsuo Satake
Keyword(s):  
Calcium Paradox ◽  
Isolated Ventricle
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