Isolation and characterization of mouse neural precursor cells in primary culture

1991 ◽  
Vol 27 (8) ◽  
pp. 615-624 ◽  
Author(s):  
Hiroshi Kitani ◽  
Robert Shiurba ◽  
Teruyo Sakakura ◽  
Yasuhiro Tomooka
Keyword(s):  
Primary Culture ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Isolation And Characterization

Isolation and characterization of neural precursor cells from theSox1-GFP reporter mouse

2005 ◽  
Vol 22 (7) ◽  
pp. 1555-1569 ◽  
Author(s):  
Perrine Barraud ◽  
Lachlan Thompson ◽  
Deniz Kirik ◽  
Anders Björklund ◽  
Malin Parmar
Keyword(s):  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Reporter Mouse ◽  
Isolation And Characterization ◽  
Gfp Reporter

scholarly journals Characterization of glycoconjugate antigens in mouse embryonic neural precursor cells

2005 ◽  
Vol 95 (5) ◽  
pp. 1311-1320 ◽  
Author(s):  
Makoto Yanagisawa ◽  
Tetsuya Taga ◽  
Kazuo Nakamura ◽  
Toshio Ariga ◽  
Robert K. Yu
Keyword(s):  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor

scholarly journals Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments

1992 ◽  
Vol 103 (2) ◽  
pp. 589-597 ◽  
Author(s):  
J. Dahlstrand ◽  
L.B. Zimmerman ◽  
R.D. McKay ◽  
U. Lendahl
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Intermediate Filaments ◽  
Intermediate Filament ◽  
Evolutionary Relationship ◽  
Neuronal Cell ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor

Multipotential stem cells in the neural tube give rise to the different neuronal cell types found in the brain. Abrupt changes in intermediate filament gene expression accompany this transition out of the precursor state: transcription of the intermediate filament nestin is replaced by that of the neurofilaments. In order to identify human neural precursor cells, and to learn more about the evolution of the intermediate filaments expressed in the central nervous system, we have isolated the human nestin gene. Despite considerable divergence between the human and rat nestin genes, in particular in the repetitive parts of the carboxy-terminal region, the positions of the introns are perfectly conserved. Two of the three intron positions are also shared by the neurofilaments, but not by other classes of intermediate filaments. This implies that nestin and the neurofilaments had a common ancestor after branching off from the other classes of intermediate filaments, and that nestin separated from the neurofilament branch before the different neurofilament genes diverged. The characterization of human nestin also facilitates the identification of human multipotential neural precursor cells. This will be of importance for central nervous system (CNS) tumor diagnosis and transplant-based clinical approaches to human neurodegenerative diseases.

scholarly journals Molecular Characterization of cDNA Encoding a Novel Protein Related to Transcriptional Enhancer Factor-1 from Neural Precursor Cells

1995 ◽  
Vol 270 (31) ◽  
pp. 18649-18654 ◽  
Author(s):  
Michio Yasunami ◽  
Kazuo Suzuki ◽  
Takeshi Houtani ◽  
Tetsuo Sugimoto ◽  
Hiroaki Ohkubo
Keyword(s):  
Molecular Characterization ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Transcriptional Enhancer ◽  
Novel Protein ◽  
Enhancer Factor

Characterization of long-term mouse brain aggregating cultures: Evidence for maintenance of neural precursor cells

2004 ◽  
Vol 474 (2) ◽  
pp. 246-260 ◽  
Author(s):  
C. Mikaela D. Berglund ◽  
Johan Aarum ◽  
Samantha L. Budd Haeberlein ◽  
Jens R. Nyengaard ◽  
Tomas Hökfelt ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor

In Vitro Characterization of Trophic Factor Expression in Neural Precursor Cells

2012 ◽  
Vol 21 (3) ◽  
pp. 432-447 ◽  
Author(s):  
Gregory W.J. Hawryluk ◽  
Andrea J. Mothe ◽  
Mahmood Chamankhah ◽  
Jian Wang ◽  
Charles Tator ◽  
...  
Keyword(s):  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Trophic Factor ◽  
Neural Precursor ◽  
In Vitro Characterization ◽  
Factor Expression
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