Visualization of patient-specific volume images in image-guided diagnosis and therapy

Abstract:Expert systems in medicine are frequently restricted to assisting the physician to derive a patient-specific diagnosis and therapy proposal. In many cases, however, there is a clinical need to use these patient data for other purposes as well. The intention of this paper is to show how and to what extent patient data in expert systems can additionally be used to create clinical registries and for statistical data analysis. At first, the pitfalls of goal-oriented mechanisms for the multiple usability of data are shown by means of an example. Then a data acquisition and inference mechanism is proposed, which includes a procedure for controlling selection bias, the so-called knowledge-based attribute selection. The functional view and the architectural view of expert systems suitable for the multiple usability of patient data is outlined in general and then by means of an application example. Finally, the ideas presented are discussed and compared with related approaches.

Download Full-text

Intra-Abdominal Abscesses: Emphasis on Image-Guided Diagnosis and Therapy

Journal of Intensive Care Medicine ◽

10.1046/j.1525-1489.1998.00320.x ◽

1998 ◽

Vol 13 (6) ◽

pp. 320-328 ◽

Cited By ~ 1

Author(s):

Thomas G. Gleason ◽

Timothy L. Pruett ◽

Robert G. Sawyer ◽

Keyword(s):

Image Guided ◽

Diagnosis And Therapy ◽

Abdominal Abscesses

Download Full-text

NIMG-33CORRELATING A PATIENT-SPECIFIC MATHEMATICAL MODEL OF GLIOBLASTOMA PROLIFERATION-INVASION WITH IMAGE-GUIDED BIOPSIES

Neuro-Oncology ◽

10.1093/neuonc/nov225.33 ◽

2015 ◽

Vol 17 (suppl 5) ◽

pp. v161.1-v161

Author(s):

Andrea Hawkins-Daarud ◽

Hani Malone ◽

Timothy Ung ◽

Anthony Rosenberg ◽

Joshua Jacobs ◽

...

Keyword(s):

Mathematical Model ◽

Patient Specific ◽

Image Guided

Download Full-text

Integrated multi-modality image-guided navigation for neurosurgery: open-source software platform using state-of-the-art clinical hardware

International Journal of Computer Assisted Radiology and Surgery ◽

10.1007/s11548-021-02374-5 ◽

2021 ◽

Author(s):

Jonathan Shapey ◽

Thomas Dowrick ◽

Rémi Delaunay ◽

Eleanor C. Mackle ◽

Stephen Thompson ◽

...

Keyword(s):

Skull Base ◽

Open Source ◽

Open Source Software ◽

Skull Base Surgery ◽

Patient Specific ◽

Software Platform ◽

Image Guided ◽

Phantom Model ◽

Technical Requirements ◽

Navigated Ultrasound

Abstract Purpose Image-guided surgery (IGS) is an integral part of modern neuro-oncology surgery. Navigated ultrasound provides the surgeon with reconstructed views of ultrasound data, but no commercial system presently permits its integration with other essential non-imaging-based intraoperative monitoring modalities such as intraoperative neuromonitoring. Such a system would be particularly useful in skull base neurosurgery. Methods We established functional and technical requirements of an integrated multi-modality IGS system tailored for skull base surgery with the ability to incorporate: (1) preoperative MRI data and associated 3D volume reconstructions, (2) real-time intraoperative neurophysiological data and (3) live reconstructed 3D ultrasound. We created an open-source software platform to integrate with readily available commercial hardware. We tested the accuracy of the system’s ultrasound navigation and reconstruction using a polyvinyl alcohol phantom model and simulated the use of the complete navigation system in a clinical operating room using a patient-specific phantom model. Results Experimental validation of the system’s navigated ultrasound component demonstrated accuracy of $$<4.5\,\hbox {mm}$$ < 4.5 mm and a frame rate of 25 frames per second. Clinical simulation confirmed that system assembly was straightforward, could be achieved in a clinically acceptable time of $$<15\,\hbox {min}$$ < 15 min and performed with a clinically acceptable level of accuracy. Conclusion We present an integrated open-source research platform for multi-modality IGS. The present prototype system was tailored for neurosurgery and met all minimum design requirements focused on skull base surgery. Future work aims to optimise the system further by addressing the remaining target requirements.

Download Full-text