Rhinal cortex and hippocampus interact synchronically in human memory formation

2002 ◽  
Vol 249 (2) ◽  
pp. 237-239
eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Catherine M Sweeney-Reed ◽  
Tino Zaehle ◽  
Jürgen Voges ◽  
Friedhelm C Schmitt ◽  
Lars Buentjen ◽  
...  

Previously we reported electrophysiological evidence for a role for the anterior thalamic nucleus (ATN) in human memory formation (<xref ref-type="bibr" rid="bib29">Sweeney-Reed et al., 2014</xref>). Theta-gamma cross-frequency coupling (CFC) predicted successful memory formation, with the involvement of gamma oscillations suggesting memory-relevant local processing in the ATN. The importance of the theta frequency range in memory processing is well-established, and phase alignment of oscillations is considered to be necessary for synaptic plasticity. We hypothesized that theta phase alignment in the ATN would be necessary for memory encoding. Further analysis of the electrophysiological data reveal that phase alignment in the theta rhythm was greater during successful compared with unsuccessful encoding, and that this alignment was correlated with the CFC. These findings support an active processing role for the ATN during memory formation.


NeuroImage ◽  
2016 ◽  
Vol 138 ◽  
pp. 100-108 ◽  
Author(s):  
Catherine M. Sweeney-Reed ◽  
Tino Zaehle ◽  
Jürgen Voges ◽  
Friedhelm C. Schmitt ◽  
Lars Buentjen ◽  
...  

10.1038/7221 ◽  
1999 ◽  
Vol 2 (4) ◽  
pp. 311-314 ◽  
Author(s):  
Randy L. Buckner ◽  
William M. Kelley ◽  
Steven E. Petersen

10.1038/nn759 ◽  
2001 ◽  
Vol 4 (12) ◽  
pp. 1259-1264 ◽  
Author(s):  
Jürgen Fell ◽  
Peter Klaver ◽  
Klaus Lehnertz ◽  
Thomas Grunwald ◽  
Carlo Schaller ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-10 ◽  
Author(s):  
Naoyuki Sato ◽  
Yoko Yamaguchi

The episodic memory, the memory of personal events and history, is essential for understanding the mechanism of human intelligence. Neuroscience evidence has shown that the hippocampus, a part of the limbic system, plays an important role in the encoding and the retrieval of the episodic memory. This paper reviews computational models of the hippocampus and introduces our own computational model of human episodic memory based on neural synchronization. Results from computer simulations demonstrate that our model provides advantage for instantaneous memory formation and selective retrieval enabling memory search. Moreover, this model was found to have the ability to predict human memory recall by integrating human eye movement data during encoding. The combined approach between computational models and experiment is efficient for theorizing the human episodic memory.


2014 ◽  
Author(s):  
Catherine M Sweeney-Reed ◽  
Tino Zaehle ◽  
Juergen Voges ◽  
Friedhelm C Schmitt ◽  
Lars Buentjen ◽  
...  

2004 ◽  
Vol 16 (1) ◽  
pp. 139-148 ◽  
Author(s):  
Gagan S. Wig ◽  
Michael B. Miller ◽  
Alan Kingstone ◽  
William M. Kelley

The present study used fMRI to investigate functional dissociations across frontal regions during incidental memory formation. Subjects were imaged while encoding materials with differential access to phonological codes (nonfamous faces and nameable famous faces) under task conditions that encouraged elaborate (deep) or superficial (shallow) encoding strategies. Results revealed a functional dissociation between dorsal posterior regions of the prefrontal cortex (BA 6/44) that were sensitive to material type (famous vs. nonfamous), irrespective of the encoding task, and ventral anterior regions of the prefrontal cortex (BA 45/47) that were uniquely sensitive to task demands (deep vs. shallow), regardless of material type. Further, subjects realized a memorial advantage to the extent that they recruited these dissociable frontal regions. These results demonstrate a posterior/anterior dichotomy in the frontal cortex that underlies separable code-based routes to human memory formation.


Author(s):  
Catherine M Sweeney-Reed ◽  
Tino Zaehle ◽  
Jürgen Voges ◽  
Friedhelm C Schmitt ◽  
Lars Buentjen ◽  
...  

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