scholarly journals A novel family of katanin-like 2 protein isoforms (KATNAL2), interacting with nucleotide-binding proteins Nubp1 and Nubp2, are key regulators of different MT-based processes in mammalian cells

2015 ◽  
Vol 73 (1) ◽  
pp. 163-184 ◽  
Author(s):  
Antonis Ververis ◽  
Andri Christodoulou ◽  
Maria Christoforou ◽  
Christina Kamilari ◽  
Carsten W. Lederer ◽  
...  
Keyword(s):  
Mammalian Cells ◽  
Binding Proteins ◽  
Nucleotide Binding ◽  
Protein Isoforms ◽  
Nucleotide Binding Proteins

scholarly journals Cellular roles of the human Obg-like ATPase 1 (hOLA1) and its YchF homologs

2020 ◽  
Vol 98 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Nirujah Balasingam ◽  
Harland E. Brandon ◽  
Joseph A. Ross ◽  
Hans-Joachim Wieden ◽  
Nehal Thakor
Keyword(s):  
Stress Response ◽  
Mammalian Cells ◽  
Binding Proteins ◽  
Mrna Translation ◽  
Nucleotide Binding ◽  
Structure And Function ◽  
Cellular Stress Response ◽  
Related Family ◽  
And Function ◽  
Nucleotide Binding Proteins

P-loop NTPases comprise one of the major superfamilies of nucleotide binding proteins, which mediate a variety of cellular processes, such as mRNA translation, signal transduction, cell motility, and growth regulation. In this review, we discuss the structure and function of two members of the ancient Obg-related family of P-loop GTPases: human Obg-like ATPase 1 (hOLA1), and its bacterial/plant homolog, YchF. After a brief discussion of nucleotide binding proteins in general and the classification of the Obg-related family in particular, we discuss the sequence and structural features of YchF and hOLA1. We then explore the various functional roles of hOLA1 in mammalian cells during stress response and cancer progression, and of YchF in bacterial cells. Finally, we directly compare and contrast the structure and function of hOLA1 with YchF before summarizing the future perspectives of hOLA1 research. This review is timely, given the variety of recent studies aimed at understanding the roles of hOLA1 and YchF in such critical processes as cellular-stress response, oncogenesis, and protein synthesis.

scholarly journals Changes in the guanine nucleotide-binding proteins, Gi and go , during differentiation of 3T3-L1 cells

FEBS Letters ◽  
1986 ◽  
Vol 199 (1) ◽  
pp. 103-106 ◽  
Author(s):  
Peter Gierschik ◽  
Bernice Morrow ◽  
Graeme Milligan ◽  
Charles Rubin ◽  
Allen Spiegel
Keyword(s):  
Binding Proteins ◽  
Nucleotide Binding ◽  
Guanine Nucleotide ◽  
Guanine Nucleotide Binding ◽  
Nucleotide Binding Proteins ◽  
Guanine Nucleotide Binding Proteins

scholarly journals Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins

1997 ◽  
Vol 4 (3) ◽  
pp. 231-238 ◽  
Author(s):  
Charles Brenner ◽  
Preston Garrison ◽  
Jeffrey Gilmour ◽  
Daniel Peisach ◽  
Dagmar Ringe ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Binding Proteins ◽  
Nucleotide Binding ◽  
Nucleotide Binding Proteins
Sign in / Sign up

Export Citation Format

Share Document