Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole

2021 ◽  
Author(s):  
Jephte Y. Akakpo ◽  
Matthew W. Jaeschke ◽  
Anup Ramachandran ◽  
Steven C. Curry ◽  
Barry H. Rumack ◽  
...  
Keyword(s):  
Acetaminophen Overdose

scholarly journals Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

2009 ◽  
Vol 37 (8) ◽  
pp. 1779-1784 ◽  
Author(s):  
Laura P. James ◽  
Lynda Letzig ◽  
Pippa M. Simpson ◽  
Edmund Capparelli ◽  
Dean W. Roberts ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Protein Adducts ◽  
Acetaminophen Overdose

scholarly journals Benzyl Alcohol: A novel treatment for acetaminophen overdose?

Hepatology ◽  
2015 ◽  
Vol 62 (5) ◽  
pp. 1641-1642 ◽  
Author(s):  
Hartmut Jaeschke ◽  
Kuo Du
Keyword(s):  
Benzyl Alcohol ◽  
Acetaminophen Overdose ◽  
Novel Treatment

Case Report: Recognition of Nonhepatic Coma in the Setting of Acetaminophen Overdose

2004 ◽  
Vol 49 (11-12) ◽  
pp. 1977-1980 ◽  
Author(s):  
Aftab Ala ◽  
Thomas Schiano ◽  
Andrew Burroughs ◽  
Satish Keshav
Keyword(s):  
Case Report ◽  
Acetaminophen Overdose

Acetaminophen Overdose as a Suicidal Gesture: A Survey of Adolescents' Knowledge of Its Potential for Toxicity

1992 ◽  
Vol 31 (4) ◽  
pp. 686-690 ◽  
Author(s):  
WADE C. MYERS ◽  
TERRANCE A. OTTO ◽  
ELAINE HARRIS ◽  
DANIEL DIACO ◽  
ANTHONY MORENO
Keyword(s):  
Acetaminophen Overdose

Cimetidine in the Treatment of Acetaminophen Overdose

1991 ◽  
Vol 13 (1) ◽  
pp. 79-82 ◽  
Author(s):  
Gary C. Rolband ◽  
Stefan P. Marcuard
Keyword(s):  
Acetaminophen Overdose

Acetaminophen overdose

Reactions ◽  
1980 ◽  
Vol 21 (1) ◽  
pp. 3-3
Keyword(s):  
Acetaminophen Overdose

ACETAMINOPHEN OVERDOSE AS A SUICIDAL GESTURE: A SURVEY OF ADOLESCENTS' KNOWLEDGE OF ITS POTENTIAL FOR TOXICITY

PEDIATRICS ◽  
1994 ◽  
Vol 93 (6) ◽  
pp. A36-A36
Author(s):  
Wade C. Myers ◽  
Terrance A. Otto ◽  
Elaine Harris ◽  
Daniel Diaco ◽  
Anthony Moreno
Keyword(s):  
High School ◽  
High School Students ◽  
School Students ◽  
Acetaminophen Overdose ◽  
Early Symptoms ◽  
Item Questionnaire ◽  
Widespread Availability ◽  
Lack Of Knowledge

Acetaminophen is a popular nonprescription analgesic that is often taken in overdose by adolescents during suicidal gestures. The authors hypothesized that most adolescents are naive about the toxic and lethal potential of acetaminophen in overdose. A one-page, 12-item questionnaire was administered to 169 high school students to evaluate their perceptions and knowledge in this area. Whereas only 22% of the sample underestimated the dose of acetaminophen necessary to cause harm, 40.5% underestimated the potential lethality of acetaminophen in overdose. Moreover, 17% of the sample did not believe one could ingest enough acetaminophen to cause death. The lack of knowledge about acetaminophen's potential dangerousness, its widespread availability, and an absence of early symptoms of hepatotoxicity make this medication highly dangerous to those adolescents who take it in overdose during parasuicidal behavior.

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