The effects of the dopamine D2/3 agonist quinpirole on incentive value and palatability-based choice in a rodent model of attention-deficit/hyperactivity disorder

2021 ◽  
Author(s):  
Joman Y. Natsheh ◽  
Diego Espinoza ◽  
Shaznaan Bhimani ◽  
Michael William Shiflett
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Rodent Model ◽  
Hyperactivity Disorder ◽  
Dopamine D2 ◽  
Incentive Value

Schizophrenia, Parkinson’s disease, and attention deficit hyperactivity disorder

2018 ◽  
Author(s):  
Richard J. Beninger
Keyword(s):  
Parkinson’S Disease ◽  
Attention Deficit Hyperactivity Disorder ◽  
Parkinson's Disease ◽  
Attention Deficit ◽  
Antipsychotic Treatment ◽  
Incentive Learning ◽  
Dopaminergic Drugs ◽  
Dopaminergic Neurotransmission ◽  
Hyperactivity Disorder ◽  
Incentive Value

Schizophrenia, Parkinson’s disease, and attention deficit hyperactivity disorder (ADHD) discusses how hyperactive dopaminergic neurotransmission appears to underlie schizophrenia’s positive symptoms, loss of dopaminergic neurons in adulthood leads to Parkinson’s disease, and dopamine neuron hypofunction in childhood and adolescence may underlie ADHD. Positive schizophrenia symptoms may arise from excessive incentive learning that is gradually lost with antipsychotic treatment. Declarative learning and memory may contribute to delusions based on excessive incentive learning. Loss of responsiveness to environmental stimuli in Parkinson’s may result from a decrease of their conditioned incentive value and inverse incentive learning. Conditioned incentive stimuli not encountered while in a state of decreased dopaminergic neurotransmission may retain their incentive value, producing apparent kinesia paradoxa. Dopamine hypofunction in juveniles does not lead to hypokinesia but may result in loss of incentive learning that focuses attention. Pro-dopaminergic drugs have a calming effect in ADHD, presumably because they reinstate normal incentive learning.

scholarly journals Adolescent d-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood

2016 ◽  
Vol 233 (23-24) ◽  
pp. 3891-3903 ◽  
Author(s):  
Chloe J. Jordan ◽  
Carley Lemay ◽  
Linda P. Dwoskin ◽  
Kathleen M. Kantak
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Cocaine Abuse ◽  
Rodent Model ◽  
Hyperactivity Disorder ◽  
Amphetamine Treatment

scholarly journals Altered visual processing in a rodent model of Attention-Deficit Hyperactivity Disorder

Neuroscience ◽  
2015 ◽  
Vol 303 ◽  
pp. 364-377 ◽  
Author(s):  
L.R. Brace ◽  
I. Kraev ◽  
C.L. Rostron ◽  
M.G Stewart ◽  
P.G. Overton ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Visual Processing ◽  
Rodent Model ◽  
Hyperactivity Disorder

scholarly journals Auditory responses in a rodent model of Attention Deficit Hyperactivity Disorder

2015 ◽  
Vol 1629 ◽  
pp. 10-25 ◽  
Author(s):  
Louise R. Brace ◽  
Igor Kraev ◽  
Claire L. Rostron ◽  
Michael G. Stewart ◽  
Paul G. Overton ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Rodent Model ◽  
Hyperactivity Disorder ◽  
Auditory Responses

scholarly journals Extinction learning deficit in a rodent model of attention-deficit hyperactivity disorder

2012 ◽  
Vol 8 (1) ◽  
pp. 59 ◽  
Author(s):  
Ryan J Brackney ◽  
Timothy HC Cheung ◽  
Katrina Herbst ◽  
Jade C Hill ◽  
Federico Sanabria
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Rodent Model ◽  
Learning Deficit ◽  
Extinction Learning ◽  
Hyperactivity Disorder

scholarly journals Conditioned inhibition in a rodent model of attention-deficit/hyperactivity disorder.

2011 ◽  
Vol 125 (6) ◽  
pp. 979-987 ◽  
Author(s):  
John T. Green ◽  
Amy C. Chess ◽  
Cynthia J. Conquest ◽  
Brittney A. Yegla
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Conditioned Inhibition ◽  
Rodent Model ◽  
Hyperactivity Disorder
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