Smooth pursuit rather than visual signals mediate short-term adaptation of the cervico-ocular reflex in humans

2005 ◽  
Vol 169 (2) ◽  
pp. 153-161 ◽  
Author(s):  
D. Mandellos ◽  
D. Anastasopoulos ◽  
W. Becker
Keyword(s):  
Smooth Pursuit ◽  
Visual Signals ◽  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation

Role of the Dorsolateral Pontine Nucleus in Short-Term Adaptation of the Horizontal Vestibuloocular Reflex

2003 ◽  
Vol 89 (5) ◽  
pp. 2879-2885 ◽  
Author(s):  
Seiji Ono ◽  
Vallabh E. Das ◽  
Michael J. Mustari
Keyword(s):  
Smooth Pursuit ◽  
Head Rotation ◽  
Visual Signals ◽  
Adaptation Period ◽  
Short Term ◽  
Accessory Optic System ◽  
Pontine Nucleus ◽  
Short Term Adaptation ◽  
Dorsolateral Pontine Nucleus

The dorsolateral pontine nucleus (DLPN) is a major component of the cortico-ponto-cerebellar pathway that carries signals essential for smooth pursuit. This pathway also carries visual signals that could play a role in visually guided motor learning in the vestibular ocular reflex (VOR). However, there have been no previous studies that tested this possibility directly. The aim of this study was to determine the potential role of the DLPN in short-term VOR gain adaptation produced by viewing a scene through lenses placed in front of both eyes. In control experiments, adaptation of VOR gain was achieved by sinusoidal rotation (0.2 Hz, 30°/s) for 2 h while the monkey viewed a stationary visual surround through either magnifying (×2) or minifying (×0.5) lenses. This led to increases (23–32%) or decreases (22–48%) of VOR gain as measured in complete darkness (VORd). We used injections of muscimol, a potent GABAA agonist (0.5 μl; 2%), to reversibly inactivate the DLPN, unilaterally, in three monkeys. After DLPN inactivation, initial acceleration of ipsilateral smooth-pursuit was reduced by 35–68%, and steady-state gain was reduced by 32–61%. Despite these significant deficits ( P < 0.01) in ipsilesional smooth pursuit, the VOR during lens viewing was similar to that measured in preinjection control experiments. Similarly, after 2 h of adaptation, VORd gain was not significantly different ( P > 0.61) from control adaptation values for either ipsi- or contralesional directions of head rotation. This was the case even though a stable ipsilesional smooth pursuit deficit persisted throughout the full adaptation period. Our results suggest that visual error signals for short-term adaptation of the VOR are derived from sources other than the DLPN perhaps including other basilar pontine nuclei and the accessory optic system.

scholarly journals Asymmetric short-term adaptation of the vertical vestibulo-ocular reflex in humans

2006 ◽  
Vol 172 (3) ◽  
pp. 343-350 ◽  
Author(s):  
Sarah Marti ◽  
Christopher J. Bockisch ◽  
Dominik Straumann
Keyword(s):  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation ◽  
Vestibulo Ocular Reflex

scholarly journals Short-term adaptation of saccades does not affect smooth pursuit eye movement initiation

2017 ◽  
Vol 17 (9) ◽  
pp. 19 ◽  
Author(s):  
Zongpeng Sun ◽  
Aleksandra Smilgin ◽  
Marc Junker ◽  
Peter W. Dicke ◽  
Peter Thier
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Short Term ◽  
Movement Initiation ◽  
Smooth Pursuit Eye Movement ◽  
Short Term Adaptation

Aging reduces the high-frequency and short-term adaptation of the vestibulo-ocular reflex in mice

2017 ◽  
Vol 51 ◽  
pp. 122-131 ◽  
Author(s):  
Serajul I. Khan ◽  
Patrick P. Hübner ◽  
Alan M. Brichta ◽  
Doug W. Smith ◽  
Americo A. Migliaccio
Keyword(s):  
High Frequency ◽  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation ◽  
Vestibulo Ocular Reflex

Context-specific short-term adaptation of the phase of the vestibulo-ocular reflex

1998 ◽  
Vol 120 (2) ◽  
pp. 184-192 ◽  
Author(s):  
P. D. Kramer ◽  
Mark Shelhamer ◽  
Grace C. Y. Peng ◽  
David S. Zee
Keyword(s):  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation ◽  
Vestibulo Ocular Reflex ◽  
Context Specific

Dynamics of the human linear vestibulo-ocular reflex at medium frequency and modification by short-term training

2000 ◽  
Vol 10 (6) ◽  
pp. 271-282 ◽  
Author(s):  
Mark Shelhamer ◽  
Dale C. Roberts ◽  
David S. Zee
Keyword(s):  
Slow Component ◽  
Phase Changes ◽  
Slow Phase ◽  
Medium Frequency ◽  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation ◽  
Vestibulo Ocular Reflex ◽  
Catch Up ◽  
Saccadic Responses

We study here the effect of a short-term training paradigm on the gain and phase of the human translational VOR (the linear VOR: LVOR). Subjects were exposed to lateral sinusoidal translations on a sled, at 0.5 Hz, 0.3 g peak acceleration. With subjects tracking a remembered target at 1.2 m, the LVOR (slow-phase) under these conditions typically has a phase lead or lag, and a gain that falls short of compensatory. To induce short-term adaptation (training), we presented an earth-fixed visual scene at 1.2 m during sinusoidal translation ( × 1 viewing) for 20 minutes, so as to drive the LVOR toward compensatory phase and gain. We examined both the slow-phase and the saccadic responses to these stimuli. Testing after training showed changes in slow-component gain and phase which were mostly but not always in the compensatory direction. These changes were more consistent in naive subjects than in subjects who had previous LVOR experience. Changes in gain were seen with step as well as sinusoidal test stimuli; gain changes were not correlated with vergence changes. There was a strong correlation between gain changes and phase changes across subjects. Fast phases (catch-up saccades) formed a large component of the LVOR under our testing conditions (approximately 30% of the changes in gain but not in phase due to training.

Short-term adaptation of the cervico-ocular reflex

2004 ◽  
Vol 156 (1) ◽  
pp. 124-128 ◽  
Author(s):  
D. C. Rijkaart ◽  
J. N. van der Geest ◽  
W. P. Kelders ◽  
C. I. de Zeeuw ◽  
M. A. Frens
Keyword(s):  
Short Term ◽  
Ocular Reflex ◽  
Short Term Adaptation

Short-term adaptation to auditory-visual discordance: The ventriloquism aftereffect

2001 ◽  
Author(s):  
Jean Vroomen ◽  
Paul Bertelson ◽  
Ilja Frissen ◽  
Beatrice De Gelder
Keyword(s):  
Short Term ◽  
Short Term Adaptation ◽  
Ventriloquism Aftereffect
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