Robotic-assisted transrectal MRI-guided biopsy. Technical feasibility and role in the current diagnosis of prostate cancer: an initial single-center experience

2020 ◽  
Vol 45 (12) ◽  
pp. 4150-4159
Author(s):  
Joan C. Vilanova ◽  
Anna Pérez de Tudela ◽  
Josep Puig ◽  
Martijn Hoogenboom ◽  
Joaquim Barceló ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Single Center ◽  
Technical Feasibility ◽  
Robotic Assisted ◽  
Single Center Experience ◽  
Guided Biopsy ◽  
Mri Guided

scholarly journals Diagnostic performance of 68Ga-PSMA-11 PET/MRI-guided biopsy in patients with suspected prostate cancer: a prospective single-center study

2021 ◽  
Author(s):  
Daniela A. Ferraro ◽  
Anton S. Becker ◽  
Benedikt Kranzbühler ◽  
Iliana Mebert ◽  
Anka Baltensperger ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
High Accuracy ◽  
Emission Tomography ◽  
Single Center ◽  
Resonance Imaging ◽  
Guided Biopsy ◽  
Positron Emission ◽  
Psma Pet ◽  
Mri Guided

Abstract Purpose Ultrasound-guided biopsy (US biopsy) with 10–12 cores has a suboptimal sensitivity for clinically significant prostate cancer (sigPCa). If US biopsy is negative, magnetic resonance imaging (MRI)–guided biopsy is recommended, despite a low specificity for lesions with score 3–5 on Prostate Imaging Reporting and Data System (PIRADS). Screening and biopsy guidance using an imaging modality with high accuracy could reduce the number of unnecessary biopsies, reducing side effects. The aim of this study was to assess the performance of positron emission tomography/MRI with 68Ga-labeled prostate-specific membrane antigen (PSMA-PET/MRI) to detect and localize primary sigPCa (ISUP grade group 3 and/or cancer core length ≥ 6 mm) and guide biopsy. Methods Prospective, open-label, single-center, non-randomized, diagnostic accuracy study including patients with suspected PCa by elevation of prostate-specific antigen (PSA) level and a suspicious lesion (PIRADS ≥3) on multiparametric MRI (mpMRI). Forty-two patients underwent PSMA-PET/MRI followed by both PSMA-PET/MRI-guided and section-based saturation template biopsy between May 2017 and February 2019. Primary outcome was the accuracy of PSMA-PET/MRI for biopsy guidance using section-based saturation template biopsy as the reference standard. Results SigPCa was found in 62% of the patients. Patient-based sensitivity, specificity, negative and positive predictive value, and accuracy for sigPCa were 96%, 81%, 93%, 89%, and 90%, respectively. One patient had PSMA-negative sigPCa. Eight of nine false-positive lesions corresponded to cancer on prostatectomy and one in six false-negative lesions was negative on prostatectomy. Conclusion PSMA-PET/MRI has a high accuracy for detecting sigPCa and is a promising tool to select patients with suspicion of PCa for biopsy. Trial registration This trial was retrospectively registered under the name “Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men with Elevated PSA” (NCT03187990) on 06/15/2017 (https://clinicaltrials.gov/ct2/show/NCT03187990).

Robotic-assisted radical prostatectomy with the Senhance® robotic platform: single center experience

2021 ◽  
Author(s):  
Raimundas Venckus ◽  
Marius Jasenas ◽  
Titas Telksnys ◽  
Martynas Venckus ◽  
Vinsas Janusonis ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Single Center ◽  
Robotic Platform ◽  
Robotic Assisted ◽  
Single Center Experience ◽  
Robotic Assisted Radical Prostatectomy

scholarly journals Use of MRI-Guided Biopsy for Selection and Follow-up of Men Undergoing Hemi-gland Cryoablation of Prostate Cancer

Urology ◽  
2019 ◽  
Vol 126 ◽  
pp. 158-164 ◽  
Author(s):  
Steve R. Zhou ◽  
Demetrios N. Simopoulos ◽  
Rajiv Jayadevan ◽  
Ely R. Felker ◽  
Merdie K. Delfin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Guided Biopsy ◽  
Mri Guided

MRI-guided Biopsy in Active Surveillance of Prostate Cancer

2021 ◽  
Author(s):  
Adam Kinnaird ◽  
Nitin K. Yerram ◽  
Luke O’Connor ◽  
Wayne Brisbane ◽  
Vidit Sharma ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Guided Biopsy ◽  
Mri Guided
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