Combination of doxorubicin and low-intensity ultrasound causes a synergistic enhancement in cell killing and an additive enhancement in apoptosis induction in human lymphoma U937 cells

2007 ◽  
Vol 61 (4) ◽  
pp. 559-567 ◽  
Author(s):  
Toru Yoshida ◽  
Takashi Kondo ◽  
Ryohei Ogawa ◽  
Loreto B. Feril ◽  
Qing-Li Zhao ◽  
...  
2007 ◽  
Author(s):  
Toru Yoshida ◽  
Loreto B. Feril ◽  
Takashi Kondo ◽  
Qing-Li Zhao ◽  
Ryohei Ogawa ◽  
...  

2008 ◽  
Vol 270 (2) ◽  
pp. 286-294 ◽  
Author(s):  
Yoshiaki Tabuchi ◽  
Ichiro Takasaki ◽  
Qing-Li Zhao ◽  
Shigehito Wada ◽  
Takeshi Hori ◽  
...  

2016 ◽  
Vol 19 (3) ◽  
pp. 167-174 ◽  
Author(s):  
Mariantonietta Ivone ◽  
Carmine Pappalettere ◽  
Akiko Watanabe ◽  
Katsuro Tachibana

2016 ◽  
Vol 22 ◽  
pp. 5049-5057 ◽  
Author(s):  
Timur Saliev ◽  
Loreto B. Feril Jr. ◽  
Koichi Ogawa ◽  
Akiko Watanabe ◽  
Dinara Begimbetova ◽  
...  

APOPTOSIS ◽  
2012 ◽  
Vol 17 (6) ◽  
pp. 636-645 ◽  
Author(s):  
Da-Yong Yu ◽  
Qing-Li Zhao ◽  
Masakazu Furuta ◽  
Setsuko Todoriki ◽  
Keisuke Izumi ◽  
...  

Measurement ◽  
2021 ◽  
Vol 167 ◽  
pp. 108280
Author(s):  
Zeinab Hormozi-Moghaddam ◽  
Manijhe Mokhtari-Dizaji ◽  
Mohammad-Ali Nilforoshzadeh ◽  
Mohsen Bakhshandeh

2019 ◽  
Vol 19 (06) ◽  
pp. 1950057
Author(s):  
MARIANTONIETTA IVONE ◽  
LUCIANO LAMBERTI ◽  
CARMINE PAPPALETTERE ◽  
MARIANO FRANCESCO CARATOZZOLO ◽  
APOLLONIA TULLO

The low-intensity ultrasound effects on MCF7 (human breast adenocarcinoma) and MCF10A (healthy breast cells) have been investigated at different sonication protocol to probe the effectiveness and the selectivity of the ultrasound (US) treatment and to understand the implications between cell mortality, biomechanical interactions and cell elastic modulus. Experiments performed at fixed and variable frequency demonstrated the effectiveness of some protocols in killing carcinogenic cells and the healthy cells insensitivity. Variation of elastic properties of MCF7 cells exposed to US under varying sonication conditions was examined. Sonication was carried out at fixed frequency (as it is usually done in therapy protocols), between 400[Formula: see text]kHz and 620[Formula: see text]kHz, following two protocols: (i) at fixed power output; (ii) at fixed voltage of the US generator. Evolution of cell stiffness during the US treatment was monitored via atomic force spectroscopy (AFS). It was found that cell mortality has a similar trend of variation with respect to sonication frequency regardless of the way specimens are exposed to US. Mechanical properties do not show a uniform trend with respect to frequency, but variations of Young’s modulus are more marked near the very low (400–480) kHz or very high frequencies (580–620) kHz. The observed variations may be related to mechanical interactions occurring in the cell culture, suggesting a primacy of the environment on other factors.


1998 ◽  
Vol 355S ◽  
pp. S216-S229 ◽  
Author(s):  
Michael Hadjiargyrou ◽  
Kenneth McLeod ◽  
John P. Ryaby ◽  
Clinton Rubin

2017 ◽  
Vol 36 (8) ◽  
pp. 1693-1706
Author(s):  
Ailing Teo ◽  
Amir Morshedi ◽  
Jen-Chieh Wang ◽  
Yufeng Zhou ◽  
Mayasari Lim

Sign in / Sign up

Export Citation Format

Share Document